| Identification | Back Directory | [Name]
Biotin-PEG2-C4-Alkyne | [CAS]
1011268-28-2 | [Synonyms]
Biotin-PEG2-C4-Alkyne
1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-2-oxo-N-[2-[2-[2-[(1-oxo-5-hexyn-1-yl)amino]ethoxy]ethoxy]ethyl]-, (3aS,4S,6aR)- | [Molecular Formula]
C22H36N4O5S | [MDL Number]
MFCD28505539 | [MOL File]
1011268-28-2.mol | [Molecular Weight]
468.61 |
| Chemical Properties | Back Directory | [Boiling point ]
799.8±60.0 °C(Predicted) | [density ]
1.158±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DMF | [form ]
A crystalline solid | [pka]
13.90±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
Alkynyl-biotin is a form of biotin with a terminal alkyne group separated by two polyethylene glycol moieties. It is used to add biotin to other molecules bearing an azide group using a copper Cu(I)-catalyzed azide-alkyne cycloaddition reaction. Alkynyl-biotin has been used to add a biotin tag to a range of biochemicals, amino acids, proteins, and nucleotides that have been modified by the addition of an azide group. Alkynyl-biotin can also be used to capture sulfenic acid-modified proteins that have been tagged with the cell-permeable probe DAz-2 . |
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