| Identification | Back Directory | [Name]
Qingyangshengenin B | [CAS]
106758-54-7 | [Synonyms]
qyc5
Wilfoside C3N
Otophylloside B
Qingyangshengenin B
Pregn-5-en-20-one, 3-[(O-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-12-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-8,14,17-trihydroxy-, (3β,12β,14β,17α)- | [Molecular Formula]
C49H78O16 | [MDL Number]
MFCD30724998 | [MOL File]
106758-54-7.mol | [Molecular Weight]
923.13 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Qingyang ginseng and Artemisia annua. | [Uses]
Qingyang ginseng aglycone B has the functions of calming the liver and tonifying the kidney, removing phlegm and relieving spasm. | [Definition]
ChEBI:Otophylloside B is a steroid saponin that is 17alpha-pregnenolone which is substituted by hydroxy groups at positions 8, 12beta, 14beta and 17beta, in which the 14beta-hydrocy group has been acylated by formal condensation with the carboxy group of (2E)-3,4-dimethylpent-2-enoic acid, and in which the hydroxy group at position 3 has been glycosylated with 2,6-dideoxy-3-O-methyl-beta-D-arabino-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranos. A C-21 steroidal glycoside, it is the essential active ingredient of the traditional Chinese medicine Qingyangshen, isolated from Cynanchum otophyllum and used to treat epilepsy and rheumatic pain. It has a role as a plant metabolite and an anticonvulsant. It is an 8-hydroxy steroid, a 14beta-hydroxy steroid, a 17beta-hydroxy steroid, a steroid saponin, a trisaccharide derivative and a tertiary alpha-hydroxy ketone. | [Biological Activity]
Qingyangshengenin B C-21 steroidal glycoside isolated from Qingyangshen. It has a protective effect on Aβ toxicity and reduces Aβ deposition by reducing Aβ expression at the mRNA level. It has antiepileptic activity. |
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BioBioPha Co., Ltd.
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