ChemicalBook--->CAS DataBase List--->11032-41-0

11032-41-0

11032-41-0 Structure

11032-41-0 Structure
IdentificationBack Directory
[Name]

DIHYDROERGOTAMINE MESYLATE
[CAS]

11032-41-0
[Synonyms]

DCCK
DHETX
dihydroergotoxin
dihydro-ergotoxin
Dihydroergotoxine
9,10-Dihydroergotoxine
DIHYDROERGOTAMINE MESYLATE
Ergotoxine, dihydro- (8CI, 9CI)
DIHYDROERGOTAMINE METHANESULFONATE
DIHYDROERGOTAMINE METHANESULFONATE SALT
Indolo[4,3-fg]quinoline, ergotoxine deriv.
8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotoxine deriv.
9,10-DIHYDRO-12'-HYDROXY-2'-METHYL-5'-(PHENYLMETHYL)ERGOTAMAN-3',6',18-TRIONE MESYLATE
[Molecular Formula]

C34H41N5O8S
[MDL Number]

MFCD00058615
[MOL File]

11032-41-0.mol
[Molecular Weight]

679.78
Chemical PropertiesBack Directory
[solubility ]

methanol: 21 mg/mL
[form ]

powder
[color ]

white
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22
[Safety Statements ]

36
[WGK Germany ]

3
[RTECS ]

KE7920000
Hazard InformationBack Directory
[Originator]

Redergin,Lek
[Uses]

Cognition adjuvant.
[Manufacturing Process]

Dihydrotoxine is a mixture of three hydrogenated alkaloides of ergot spur. (Claviceps purpurea). 10 g ergotoxine (the mixture of ergocornine, ergocristine, ergocryptine 1:1:1) in 200 ml dioxane and 20 g Pd/BaSO4 were stirred at a H2 pressure 10 atmospheres at 80°C for 5 hours. The catalyst was filtered off, a filtrate was distilled to dryness in vacuum. The residue was in chloroform dissolved and shook with aluminum oxide. The Al2O3 was filtered off, the filtrate was crystallized after adding of hot benzene and cooling. Yield 6-8 g dihydroergotoxine. It crystallized with 1 mol of benzene. MP: 185°C.
[Brand name]

Alkergot (Sandoz); Circanol(3M Pharmaceuticals); Deapril (Bristol-Myers Squibb);Gerimal (Watson); Hydergine (Novartis).
[Therapeutic Function]

Vasodilator
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