| Identification | Back Directory | [Name]
Nilutamide-d6 | [CAS]
1189477-66-4 | [Synonyms]
Anandron-d6
RU 23908-d6
Nilandron-d6
Nilandrone-d6
Nilutamide-d6
RU 23908-10-d6
1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-(dimethyl-d6)imidazoline-2,5-dione
5,5-(Dimethyl-d6)-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedion | [Molecular Formula]
C12H10F3N3O4 | [MDL Number]
MFCD21363735 | [MOL File]
1189477-66-4.mol | [Molecular Weight]
317.221 |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Labeled Nilutamide, intended for use as an internal standard for the quantification of Nilutamide by GC- or LC-mass spectrometry. | [Uses]
Nonsteroidal antiandrogen. Antineoplastic (hormonal) | [Description]
Nilutamide-d6 is intended for use as an internal standard for the quantification of nilutamide by GC- or LC-MS. Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor. It reverses testosterone-induced increases in cell proliferation with an IC50 value of 412 nM in mouse mammary carcinoma cells in vitro. It has antiandrogenic activity in both intact and castrated rats, inhibiting testosterone propionate-induced prostate growth when administered at a dose of 2.5 mg/kg. Formulations containing nilutamide have been used in combination with surgical castration in the treatment of metastatic prostate cancer. | [storage]
Store at -20°C |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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