| Identification | Back Directory | [Name]
LY 2784544 | [CAS]
1229236-86-5 | [Synonyms]
CS-13
LY2874544
Tucatinib
LY 2784544
LY2784544/LY-2784544
LY2784544(gandotinib)
Gandotinib (LY2784544)
3-(4-Chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[
3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine
3-(4-chloro-2-fluorobenzyl)-2-Methyl-N-(3-Methyl-1H-pyrazol-5-yl)-8-(MorpholinoMethyl)iMidazo[1,2-b]pyridazin-6-aMine
3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine
IMidazo[1,2-b]pyridazin-6-aMine, 3-[(4-chloro-2-fluorophenyl)Methyl]-2-Methyl-N-(5-Methyl-1H-pyrazol-3-yl)-8-(4-MorpholinylMethyl)-
3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine LY 2784544 | [Molecular Formula]
C23H25ClFN7O | [MDL Number]
MFCD20482143 | [MOL File]
1229236-86-5.mol | [Molecular Weight]
469.94 |
| Chemical Properties | Back Directory | [density ]
1.45 | [storage temp. ]
Store at -20°C | [solubility ]
≥23.5 mg/mL in DMSO; insoluble in H2O; ≥5.65 mg/mL in EtOH with gentle warming and ultrasonic | [form ]
solid | [pka]
14.12±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
LY2784544 is a JAK2 inhibitor. LY2784544 may be used as a potential treatment for patients with myeloproliferative neoplasm. | [Definition]
ChEBI: Gandotinib is a member of pyridazines. | [target]
wild-type JAK2 |
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