ChemicalBook--->CAS DataBase List--->134-90-7

134-90-7

134-90-7 Structure

134-90-7 Structure
IdentificationBack Directory
[Name]

L-(+)-threo-chloramphenicol
[CAS]

134-90-7
[Synonyms]

Dextramycin
Dextromycetin
(+)-Chloramphenicol
L-threo-ChloraMphenic
L-threo-Chloramphenicol
L-threo-Chloroamphenicol
L-(+)-threo-Chloramphenicol
Chloramphenicol Impurity 23
L-threo-N-Dichloracetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
L-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
L-threo-(1S,2S)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
(1S,2S)-2-(2,2-Dichloroacetamido)-1-(4-nitrophenyl)-1,3-propanediol
N-[(αS,βS)-α-(Hydroxymethyl)-β-hydroxy-4-nitrophenethyl]dichloroacetamide
2,2-Dichloro-N-[(αS,βS)-β-hydroxy-α-hydroxymethyl-4-nitrophenethyl]acetamide
2,2-Dichloro-N-[(αS,βS)-β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide
2,2-Dichloro-N-[(1S,2S)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
[S-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [S-(R*,R*)]-
Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, L-threo-(+)- (8CI)
[EINECS(EC#)]

205-161-2
[Molecular Formula]

C11H12Cl2N2O5
[MOL File]

134-90-7.mol
[Molecular Weight]

323.13
Chemical PropertiesBack Directory
[Melting point ]

150-151 °C
[Boiling point ]

527.51°C (rough estimate)
[density ]

1.2886 (rough estimate)
[refractive index ]

1.6300 (estimate)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO (Slightly), Ethanol (Sparingly, Sonicated), Methanol (Slightly)
[form ]

Solid
[pka]

11.03±0.46(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

The S,S-stereoisomer of Chloramphenicol (C325030). Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
[Definition]

ChEBI: Chloramphenicol is an organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. It has a role as an antimicrobial agent, an antibacterial drug, a protein synthesis inhibitor, an Escherichia coli metabolite, a Mycoplasma genitalium metabolite and a geroprotector. It is an organochlorine compound, a diol, a C-nitro compound and a carboxamide.
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