| Identification | Back Directory | [Name]
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride | [CAS]
1620278-72-9 | [Synonyms]
TLR7/8 agonist-5d
8 agonist 1 dihydrochloride
TLR7/8 Agonist 1 (hydrochloride)
TLR7/8 agonist 1 (dihydrochloride)
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride | [Molecular Formula]
C22H26ClN5 | [MDL Number]
MFCD31657341 | [MOL File]
1620278-72-9.mol | [Molecular Weight]
395.94 |
| Hazard Information | Back Directory | [Biological Activity]
TLR7/8 agonist 1 dihydrochloride is a dual agonist of the toll-like receptor TLR7/TLR8. | [in vitro]
TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity.It retains TLR7- agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens. | [target]
| [storage]
Store at -20°C |
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