Identification | Back Directory | [Name]
LEPTIN, MOUSE | [CAS]
181030-10-4 | [Synonyms]
MOUSE OB OB MOUSE BETA-RMOB MURINE OB MOUSE LEPTIN MURINE LEPTIN LEPTIN, MOUSE LEPTIN, MURINE leptin from mouse REC LEPTIN (MOUSE) MURINE OBESITY PROTEIN OB GENE PRODUCT (MOUSE) RECOMBINANT MOUSE LEPTIN REC OBESE PROTEIN (MOUSE) REC OBESITY FACTOR (MOUSE) LEPTIN, MOUSE, RECOMBINANT Leptin, Mouse, Recombinant, E. coli LEPTIN, MOUSE RECOMBINANT EXPRESSED IN E . COLI | [MDL Number]
MFCD01094206 |
Hazard Information | Back Directory | [Uses]
Leptin from mouse has been used:
- to check the effect of leptin on ovulation for treating infertility in obese mice
- to check the effect of leptin on MGARP (mitochondria-localized glutamic acid-rich protein) expression in testis and follicular granular cells of mice
- to study the morphometrical changes in mouse testicular tissue upon long term exposure to leptin
| [Biochem/physiol Actions]
Leptin is a hormone produced primarily in adipocytes, although leptin mRNA has also been identified in placenta and fetal tissues, gastric tissue and liver. Its primary site of action appears to be on neurons in the hypothalamus that are involved in regulating energy balance, appetite, and body weight. Leptin increases the production of nitric oxide in endothelial cells and stimulates angiogenesis in vitro and in vivo.Human and mouse leptin share ~84% sequence identity. |
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Sigma-Aldrich
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Energy Chemical
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amyjetsci
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