ChemicalBook--->CAS DataBase List--->400647-59-8

400647-59-8

400647-59-8 Structure

400647-59-8 Structure
IdentificationBack Directory
[Name]

Doxorubicin-SMCC
[CAS]

400647-59-8
[Synonyms]

Doxorubicin-SMCC
N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
[Molecular Formula]

C39H42N2O14
[MDL Number]

MFCD32004617
[MOL File]

400647-59-8.mol
[Molecular Weight]

762.76
Questions And AnswerBack Directory
[Uses]

Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
[In vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
[Storage]

Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO, DMF
Hazard InformationBack Directory
[Description]

N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin is a maleimide attached Doxorubicin. It can conjugate with thiol containing molecules.
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