ChemicalBook--->CAS DataBase List--->40733-27-5

40733-27-5

40733-27-5 Structure

40733-27-5 Structure
IdentificationBack Directory
[Name]

3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE
[CAS]

40733-27-5
[Synonyms]

3'-O-TBDMS-dT
3'-O-(TBDMS)THYMIDINE
3'-O-t-BulyldiMethylsilyl thyMidine
3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE
3'-O-(tert-ButyldiMethylsilyl)thyMidine
3'-O-tert-butyldiMethylsilyl-2'-deoxythyMidine
Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-
1-((2R,4S,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
[Molecular Formula]

C16H28N2O5Si
[MDL Number]

MFCD01631040
[MOL File]

40733-27-5.mol
[Molecular Weight]

356.49
Chemical PropertiesBack Directory
[Melting point ]

93-94 °C
[density ]

1.17±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

9.55±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

3'-O-[tert-Butyl(dimethyl)silyl]thymidine is a nucleoside analog that is chemically stable and has been shown to be a potential biomarker for the diagnosis of fetal bovine spongiform encephalopathy (BSE). 3'-O-t-Bulyldimethylsilyl thymidine binds to basic proteins in the cell nucleus and has been shown to inhibit protein synthesis in tubule cells of the kidney and skin cancer cells.
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