| Identification | Back Directory | [Name]
NS1643 | [CAS]
448895-37-2 | [Synonyms]
NS1643, >98%
NS-1643;NS 1643
NS-1643;NS1643;NS 1643
N,N'-Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea
Urea, N,N'-bis[2-hydroxy-5-(trifluoromethyl)phenyl]- | [Molecular Formula]
C15H10F6N2O3 | [MDL Number]
MFCD08705418 | [MOL File]
448895-37-2.mol | [Molecular Weight]
380.24 |
| Chemical Properties | Back Directory | [Boiling point ]
342.3±42.0 °C(Predicted) | [density ]
1.626±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO: ≥20mg/mL | [form ]
solid | [pka]
6.84±0.13(Predicted) | [color ]
white to off-white |
| Hazard Information | Back Directory | [Uses]
NS 1643 is a human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator. | [Biological Activity]
Human ether-a-go-go related gene (hERG) K + channel activator (EC 50 = 10.5 μ M). Exhibits different molecular mechanisms of action at hERG1 and hERG2 channels. Displays antiarrhythmic activity in vitro . | [storage]
+4°C |
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| Company Name: |
SynAsst Chemical.
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| Tel: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0.htm |
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