| Identification | Back Directory | [Name]
4(3H)-Pyrimidinone, 6-methyl-2-[[2-(1-naphthalenyl)-2-oxoethyl]thio]- | [CAS]
459420-09-8 | [Synonyms]
I3MT-3
13MT-3
4(3H)-Pyrimidinone, 6-methyl-2-[[2-(1-naphthalenyl)-2-oxoethyl]thio]- | [Molecular Formula]
C17H14N2O2S | [MDL Number]
MFCD33023210 | [MOL File]
459420-09-8.mol | [Molecular Weight]
310.37 |
| Chemical Properties | Back Directory | [Boiling point ]
514.9±52.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 125 mg/mL (402.75 mM) | [pka]
7.72±0.50(Predicted) |
| Hazard Information | Back Directory | [Biological Activity]
I3MT-3 (HMPSNE) is a potent, selective and cell membrane permeable inhibitor of 3-mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM), inactive against other hydrogen sulfide/sulfanilamide sulfur enzymes. I3MT-3 targets a perthiocysteine residue located in the active site of 3MST. | [target]
IC50: 2.7 μM (3-Mercaptopyruvate sulfurtransferase (3MST)) | [storage]
Store at -20°C |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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