| Identification | Back Directory | [Name]
INTEGERRIMINE | [CAS]
480-79-5 | [Synonyms]
Squalidine
INTEGERRIMINE
Intergerrimine
(-)-Integerrimine
(15E)-12-Hydroxysenecionan-11,16-dione
(20E)-12-Hydroxysenecionan-11,16-dione
Pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl(1,6)dioxacyclododecino(2,3,4-gh)-
[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3E,5R,6R,14aR,14bR)- | [Molecular Formula]
C18H25NO5 | [MOL File]
480-79-5.mol | [Molecular Weight]
335.39 |
| Chemical Properties | Back Directory | [Melting point ]
172°C | [Boiling point ]
472.03°C (rough estimate) | [density ]
1.2250 (rough estimate) | [refractive index ]
1.5100 (estimate) | [LogP]
-1.504 (est) |
| Hazard Information | Back Directory | [Description]
A pyrrolizidine alkaloid present in several species of Senecio and Crotalaria,
being first obtained from S. integerrirnus Nutt. It yields a crystalline picrate,
m.p. 224°C and on alkaline hydrolysis forms retronecine and integerrinecic acid,
ClOH160 S, m.p. 132°C which is dibasic. | [Uses]
Integerrimine is a pyrrolizidine alkaloid from Senecio leucanthemifolius poiret which displays antimicrobial activity. | [Definition]
ChEBI:Integerrimine is a macrolide. | [References]
Manske., Can. 1. Res., 17B, 1,8 (1939)
Adams, van Doulen.,J. Arner. Chern. Soc., 75,4631 (1953)
Gellest, Mate., Austral. 1. Chern., 17, 158 (1964) |
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