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ChemicalBook--->CAS DataBase List--->52213-27-1

52213-27-1

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52213-27-1 Structure

52213-27-1 Structure
IdentificationBack Directory
[Name]

Pygenic acid A
[CAS]

52213-27-1
[Synonyms]

Pygenic acid A
PUNICALAGINS A&B(P)
3-Epicorosolic acid
2,3-Dihydroxy-12-ursen-28-oic acid
(2alpha,3alpha)-2,3-Dihydroxy-urs-12-en-28-oic acid
2α,3α-Dihydroxy-19β-methyl-30-noroleana-12-ene-28-oic acid
[Molecular Formula]

C30H48O4
[MOL File]

52213-27-1.mol
[Molecular Weight]

472.7
Chemical PropertiesBack Directory
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
Hazard InformationBack Directory
[Description]

3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction. 3-Epicorosolic acid shows both potent α-glucosidase and protein tyrosine phosphatase 1B (PTP1B) inhibitory activities with IC50 values of 30.18 and 4.08 μg/ml respectively. 3. 3-Epicorosolic acid shows mixed type inhibition against PTP1B, while it shows uncompetitive inhibition against α-glucosidase; suggests that it has potential antidiabetic activity. 4. 3-Epicorosolic acid possesses the ability to inhibit the expression of one or more inflammatory genes induced by 12-O-tetradecanoylphorbol-13 acetate in mouse skin, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.
[target]

Immunology & Inflammation related
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