| Identification | Back Directory | [Name]
Exalamide | [CAS]
53370-90-4 | [Synonyms]
HBA
HYPERAN
h.p.216
EXALAMIDE
2-Hexoxybenzamide
o-Hexyloxybenzamide
o-hexyloxy-benzamid
2-(HEXYLOXY)BENZAMIDE
2-(hexyloxy)-benzamid
2-n-hexyloxybenzamide
o-(Hexyloxy)benzamide
HBA, Hyperan, 2-(Hexyloxy)benzamide | [EINECS(EC#)]
258-504-3 | [Molecular Formula]
C13H19NO2 | [MDL Number]
MFCD00865621 | [MOL File]
53370-90-4.mol | [Molecular Weight]
221.3 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
72-74°C | [Boiling point ]
362.36°C (rough estimate) | [density ]
1.0451 (rough estimate) | [refractive index ]
1.5175 (estimate) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
15.62±0.50(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Exalamide is used as an antifungal (topical). Exalamide is a derivative of salicylamide. | [Definition]
ChEBI: An arenecarboxamide that is salicylamide in which the phenolic hydroxy group has been converted to the corresponding hexyl ether. It has been used as a topical antifungal agent. | [Originator]
Hyperan,S.S. Pharm,Japan,1980 | [Manufacturing Process]
4.6 g sodium were dissolved in 150 ml ethanol and 27.4 g (0.2 mol)
salicylamide added. The solution was refluxed gently and 24.6 g (0.2mol) nhexyl-
bromide added gradually. The mixture was refluxed for six hours, the
precipitated sodium bromide filtered off, and most of the alcohol removed by
distillation. Water was then added to the residue, and the 2-nhexyloxybenzamide
filtered off. It crystallized from 50% aqueous ethanol in
colorless crystals, MP 71°C. | [Therapeutic Function]
Antifungal |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|