| Identification | Back Directory | [Name]
K-strophanthin-beta | [CAS]
560-53-2 | [Synonyms]
Nsc4320
STROPHANTHIN
K-strophanthin-beta
.beta.-K-Strophanthin
Strophanthin K (crystalline)
.beta.-Strophanthobioside, strophanthidin-3
3β-[(4-O-β-D-Glucopyranosyl-3-O-methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide
(3β,5β)-3-{[2,6-dideoxy-4-O-(β-D-glucopyranosyl)-3-O-methyl-β-D-ribo-hexopyranosyl]oxy}-5,14-dihydroxy-19-oxocard-20(22)-enolide
Card-20(22)-enolide, 3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-xylo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-
5.beta.-Card-20(22)-enolide, 3.beta.-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-
Card-20(22)-enolide, 3-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3.beta.,5.beta.)- | [Molecular Formula]
C36H54O14 | [MOL File]
560-53-2.mol | [Molecular Weight]
710.81 |
| Chemical Properties | Back Directory | [Melting point ]
195°C | [Boiling point ]
628.39°C (rough estimate) | [density ]
1.1625 (rough estimate) | [refractive index ]
1.6130 (estimate) | [pka]
12.89±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
Strophanthin is made up of a mixture of glycosides, mainly K-strophanthin-
β, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-D-cymaro-β-D-glycoside, and K-strophanthoside, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-Dcymaro-
β-D-gluco-α-D-glycozide. It is isolated primarily from the family
Strophantus kombe. | [Uses]
Strophanthin is used in severe cardiovascular insufficiency, in particular after myocardial
infarction, for chronic cardiac insufficiency, cardiac decompensation, supraventricular
tachycardia, and ventricular arrhythmia. | [Definition]
ChEBI: K-Strophanthin-beta is a cardenolide glycoside and a steroid aldehyde. |
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