| Identification | Back Directory | [Name]
O-DESMETHYLGALANTHAMINE | [CAS]
60755-80-8 | [Synonyms]
Sanguinine
O-DESMETHYLGALANTHAMINE
O-Demethyl-galanthamine
6-O-Demethylgalanthamine
10-Methyl-galantham-1-ene-3,6-diol
10-Methyl-galantham-1-ene-3b,6-diol
(8aS)-5,6,9,10,11,12-Hexahydro-11-methyl-4aαH-benzofuro[3a,3,2-ef][2]benzazepine-3,6β-diol
(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-11-Methyl-6H-benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol
(4aS,8aS)-11-Methyl-4aα,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzoazepine-3,6β-diol | [Molecular Formula]
C16H19NO3 | [MDL Number]
MFCD07369289 | [MOL File]
60755-80-8.mol | [Molecular Weight]
273.33 |
| Chemical Properties | Back Directory | [Appearance]
Pale Yellow Powder | [Melting point ]
227-230°C (dec.) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO: soluble | [form ]
A solid | [Uses]
Sanguinine has a more potent acetylcholinesterase inhibitory activity than galanthamine due to an extra hydroxyl group available for potential interaction with acetylcholinesterase. Sanguinine, in turn, is 10-fold more selective than galanthamine for acetylcholinesterase (AChE) vs. butyrylcholinesterase (BuChE). The lack of AChE inhibitory activity of lycoramine and epinorlicoramine could be due to the occurrence of a double bond in ring C, which does not allow these alkaloids to have the same spatial configuration as the active alkaloids of this series. | [CAS DataBase Reference]
60755-80-8 |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Powder | [Uses]
A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor. | [Uses]
A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor | [Definition]
ChEBI: Sanguinine is a benzazepine. | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Henan Alfachem Co.,Ltd.
|
| Tel: |
0371-0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
|