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64706-54-3

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64706-54-3 Structure

64706-54-3 Structure
IdentificationBack Directory
[Name]

BEPRIDIL
[CAS]

64706-54-3
[Molecular Formula]

C24H34N2O
[MDL Number]

MFCD00868313
[MOL File]

64706-54-3.mol
[Molecular Weight]

366.54
Chemical PropertiesBack Directory
[Boiling point ]

bp0.1 184°; bp0.5 192°
[density ]

1.0392 (rough estimate)
[refractive index ]

nD20 1.5538
[pka]

9.21±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Thionyl chloride-->Sodium carbonate-->Zinc chloride-->Water-->Epichlorohydrin-->2-Methyl-1-propanol-->Sodium amide-->Pyrrolidine-->N-Phenylbenzylamine-->Bepridil hydrochloride
Hazard InformationBack Directory
[Definition]

ChEBI: A tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl.
[Enzyme inhibitor]

This substituted pyrrolidine (FWfree-base = 366.55 g/mol) is a calcium channel blocker that inhibits the Na+/Ca2+ exchange, exhibiting antiarrhythmic, antianginal, and vasodilatory properties. Bepridil inhibits the growth of certain brain tumors in vitro. Bepridil also binds to troponin C. Target (s) : Ca2+ channels; ATP-sensitive K+ channels; Na+-activated K+ channels.
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