| Identification | Back Directory | [Name]
(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile | [CAS]
796874-99-2 | [Synonyms]
KYP-2047
KYP-2047 >=95% (HPLC)
KYP-2047;KYP 2047;KYP2047
(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile | [Molecular Formula]
C20H25N3O2 | [MDL Number]
MFCD22201003 | [MOL File]
796874-99-2.mol | [Molecular Weight]
339.43 |
| Hazard Information | Back Directory | [Uses]
KYP-2047 may be used in prolyl endopeptidase-mediated cell signaling studies. | [Biochem/physiol Actions]
KYP-2047 is a very potent, selective inhibitor of Prolyl oligopeptidase (POP), also known as prolyl endopeptidase (PEP or PE). Ki = .023nM (porcine). KYP-2047 has been found to be neuroprotective against glutamate and oxygen, glucose deprivation in vitro. It has also been used to inhibit the formation of AcSDKP from its precursor 43-mer thymosin β4 (Tβ4). Ac-SDKP is involved in hemopoietic stem cell differentiation, is pro-angiogenic and antifibrogenic. | [storage]
Store at -20°C |
|
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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