| Identification | Back Directory | [Name]
4-(1H-IMIDAZOL-4-YLMETHYL)-1-METHYLPIPERIDINE DIHYDROBROMIDE | [CAS]
817636-54-7 | [Synonyms]
METHIMEPIP DIHYDROBROMIDE
4-(1H-IMIDAZOL-4-YLMETHYL)-1-METHYLPIPERIDINE 2HBR
4-(1H-IMIDAZOL-4-YLMETHYL)-1-METHYLPIPERIDINE DIHYDROBROMIDE | [Molecular Formula]
C10H19Br2N3 | [MDL Number]
MFCD09908999 | [MOL File]
817636-54-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
156.7-157.3 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) | [storage temp. ]
Desiccate at RT | [form ]
Powder | [Water Solubility ]
Soluble to 100 mM in water |
| Hazard Information | Back Directory | [Uses]
4-(1H-Imidazol-4-ylmethyl)-1-methylpiperidine Dihydrobromide is a salt analog of methimepip, which exhibits high affinity and agonist activity at the human histamine H3 receptor. | [Biological Activity]
Extremely selective histamine H 3 receptor agonist (pK i values are 9.0, 5.7, < 5.0 and < 5.0 for hH 3 , hH 4 , hH 1 and hH 2 receptors respectively). Potently inhibits EFS-evoked contractions of guinea pig ileum (pD 2 = 8.26). | [storage]
Desiccate at RT |
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