| Identification | Back Directory | [Name]
Bardoxolone | [CAS]
890707-28-5 | [Synonyms]
Bardoxolone Powder C9h11cln2o
2-Amino-5-chloro-N,3-dimethylbenzamide
Benzamide, 2-amino-5-chloro-N,3-dimethyl-
2-Amino-5-chloro-N,3-dimethylbenzamide 98% | [EINECS(EC#)]
618-233-7 | [Molecular Formula]
C9H11ClN2O | [MDL Number]
MFCD09030601 | [MOL File]
890707-28-5.mol | [Molecular Weight]
198.65 |
| Chemical Properties | Back Directory | [Melting point ]
130-132 °C | [Boiling point ]
308.8±42.0 °C(Predicted) | [density ]
1.239 | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
14.24±0.46(Predicted) | [color ]
Off-White to Light Brown |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white powder | [Uses]
Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription factor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPARγ. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events. |
|
|