| Identification | Back Directory | [Name]
IMIDAPRILAT | [CAS]
89371-44-8 | [Synonyms]
6366A
IMIDAPRILAT
Imidaprilate
Imidapril Diacid
(4S)-3-[(2S)-N-[(1S)-1-Carboxy-3-phenylpropyl]alanyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid
(4S)-3-{(2S)-2-[N-((1S)-1-Carboxy-3-phenylpropyl)amino]propionyl}-1-methyl-2-oxoimidazolidine-4-carboxylic Acid | [Molecular Formula]
C18H23N3O6 | [MDL Number]
MFCD00870778 | [MOL File]
89371-44-8.mol | [Molecular Weight]
377.39 |
| Chemical Properties | Back Directory | [Appearance]
White to Off-White Solid | [Melting point ]
180-1820C | [alpha ]
D19 -88.4° (c = 1 in 5% NaHCO3) | [Boiling point ]
592.1±60.0 °C(Predicted) | [density ]
1.356±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Aqueous Acid (Slightly, Heated, Sonicated), DMSO (Slightly, Heated) | [form ]
Solid | [pka]
2.17±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
Antihypertensive | [Definition]
ChEBI: Imidaprilat is a member of the class of imidazolidines that is imidapril in which the ethyl ester group has been hydrolysed to the corresponding acid group. It is the active metabolite of imidapril used to treat hypertension. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a drug metabolite. It is a dipeptide, a member of imidazolidines, a secondary amino compound, a dicarboxylic acid and a N-acylurea. It is functionally related to an imidapril. |
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