| Identification | Back Directory | [Name]
REBECCAMYCIN | [CAS]
93908-02-2 | [Synonyms]
NSC 359079
REBECCAMYCIN
dro-12-(4-o-methyl-beta-d-glucopyranosyl)-
REBECCAMYCIN, SACCHAROTHRIX AEROCOLONIGENES
5h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6h)-dione,1,11-dichloro-12,13-dihy
1,11-Dichloro-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione
5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, 1,11-dichloro-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-
7,10-Dichloro-8-(3,4-dihydroxy-6-(hydroxymethyl)-5-methoxytetrahydro-2H-pyran-2-yl)-8,9-dihydro-1H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione | [Molecular Formula]
C27H21Cl2N3O7 | [MDL Number]
MFCD01718312 | [MOL File]
93908-02-2.mol | [Molecular Weight]
570.38 |
| Hazard Information | Back Directory | [Uses]
Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. Rebeccamycin displays selective antitumour activity against several cell lines. Rebeccamycin's primary mechanism of action is via strong DNA intercalation resulting in the potent catalytic inhibition of both topoisomerases I and II. Analogues of rebecamycin have beend tested in clinical trials for cancer therapy. | [Definition]
ChEBI: An N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens. | [storage]
+4°C |
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