ChemicalBook--->CAS DataBase List--->97657-92-6

97657-92-6

97657-92-6 Structure

97657-92-6 Structure
IdentificationBack Directory
[Name]

2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
[CAS]

97657-92-6
[Synonyms]

CS-784
Dimebon 2HCl
DiMebone HCl
Latrepirdine 2HCl
DiMebone dihydrochloride
DiMeboline dihydrochloride
Latrepirdine dihydrochloride
Dimebone dihydrochloride hydrate
Dimebolin dihydrochloride hydrate
Dimeboline dihydrochloride hydrate
2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole hydrochloride
2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole,dihydrochloride
2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride
2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indoledihydrochloride
2,8-dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride
2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate
2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride ISO 9001:2015 REACH
[EINECS(EC#)]

692-160-9
[Molecular Formula]

C21H25N3.2ClH
[MDL Number]

MFCD17215933
[MOL File]

97657-92-6.mol
[Molecular Weight]

392.371
Chemical PropertiesBack Directory
[Melting point ]

220-222 °C
[storage temp. ]

Desiccate at RT
[solubility ]

H2O: ≥10mg/mL
[form ]

powder
[color ]

white to off-white
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-36/38
[Safety Statements ]

26-36/39
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Latrepirdine is an antihistamine drug used initially in Russia. Recently research have explore the potential of Latrepirdine to demonstrate activities against neurodegenerative conditions.
[Biological Activity]

Non-selective antihistamine that displays cognitive enhancing abilities. Also displays high affinity for 5-HT (particularly 5-HT 6 and 5-HT 7 ), α -adrenergic, dopaminergic, AMPA and NMDA receptors, and L-type calcium channels. Exhibits neuroprotective activity in cellular models of Alzheimer's and Huntington's disease and preserves cognitive function following administration to AF64A lesioned rats. Protects neurons against the neurotoxic action of β -amyloid fragment.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride(97657-92-6)1HNMR
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