106392-48-7
中文名称
106392-48-7
英文名称
2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-
CAS
106392-48-7
分子式
C16H20N2O2
分子量
272.34
MOL 文件
106392-48-7.mol
更新日期
2024/06/07 17:54:49
106392-48-7 结构式
基本信息
中文别名
化合物ST 271 英文别名
ST 271ST271, >98%
ST271
ST 271
ST-271
2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)-
物理化学性质
沸点468.4±45.0 °C(Predicted)
密度1.137±0.06 g/cm3(Predicted)
储存条件Sealed in dry,2-8°C
酸度系数(pKa)10.05±0.40(Predicted)
常见问题列表
生物活性
ST271是一种酪氨酸磷酸化抑制剂，抑制磷脂酶D活性。靶点
| Target | Value |
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PLD
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体外研究
ST271 partially inhibits peptide phosphorylation in the membrane preparation and in permeabilized platelets. ST271 (100 μM) causes complete inhibition of formation of inositol phosphates induced by FcγRII cross-linking, but also induces a small (< 30%) but significant inhibition of the response to thrombin and U46619.