1821122-73-9
中文名称
伊马替尼杂质72
英文名称
Imatinib Impurity 72
CAS
1821122-73-9
分子式
C53H51N12O2
分子量
888.051
MOL 文件
1821122-73-9.mol
更新日期
2023/03/20 15:41:17
1821122-73-9 结构式
基本信息
中文别名
伊马替尼杂质721-甲基-1,4-双(4-(((4-甲基-3-((4-(吡啶基-3-基)嘧啶-2-基)氨基)苯基)氨基甲酰基)苄基)哌嗪-1-基(伊马替尼杂质)
英文别名
Imatinib HImatinib Imp.R
Imatinib Impurity 72
Imatinib EP Impurity D (Imatinib Dimer)
Piperazinium, 1-methyl-1,4-bis[[4-[[[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]methyl]-
1-Methyl-1,4-bis(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium (Imatinib Impurity)
1-Methyl-1,4-bis[[4-[[[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]methyl]-piperazinium DISCONTNUED
所属类别
分析化学：药典标准品和杂质标准品应用领域
用途一
1-Methyl-1,4-bis[[4-[[[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]amino]carbonyl]phenyl]methyl]-piperazinium is an impurity of Imatinib Mesylate (G407000), a tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.