183745-81-5
中文名称
183745-81-5
英文名称
AMYLOID BETA-PROTEIN (1-15)
CAS
183745-81-5
分子式
C78H107N25O27
分子量
1826.86
MOL 文件
183745-81-5.mol
183745-81-5 结构式
基本信息
中文别名
Β淀粉样蛋白(1-15) 英文别名
Aβ1-15β-Amyloid 1-15
Amyloid β-Protein (1-15)
AMyloid b-Protein (1-15)
AMYLOID BETA-PROTEIN (1-15)
Amyloid beta-Protein (1-15) trifluoroacetate salt
H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-OH
L-Glutamine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-
物理化学性质
密度1.59±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度insoluble in EtOH; ≥182.6 mg/mL in DMSO; ≥50.7 mg/mL in H2O
形态固体
常见问题列表
生物活性
β-Amyloid (1-15) 是β-淀粉样蛋白片段。 β-淀粉样蛋白是在阿尔茨海默病患者的脑中形成淀粉样斑块的肽。靶点
Amyloid-β
体外研究
β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. .