87530-30-1
中文名称
4,7-二羟基-2-甲氧基-9,10-二氢菲
英文名称
7-Methoxy-9,10-dihydrophenanthrene-2,5-diol
CAS
87530-30-1
分子式
C15H14O3
分子量
242.27
MOL 文件
87530-30-1.mol
更新日期
2023/06/30 12:29:31
87530-30-1 结构式
基本信息
中文别名
4,7-二羟基-2-甲氧基-9,10-二氢菲 英文别名
Lusianthridin9,10-Dihydro-2-methoxyphenanthrene-4,7-diol
7-Methoxy-9,10-dihydrophenanthrene-2,5-diol
2,5-Phenanthrenediol, 9,10-dihydro-7-methoxy-
4,7-dihydroxy-2-methoxy-9,10-dihydrophenanthrene
所属类别
化学试剂：多环化合物物理化学性质
沸点507.3±50.0 °C(Predicted)
密度1.296±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
酸度系数(pKa)9.23±0.20(Predicted)
形态粉末
常见问题列表
生物活性
Lusianthridin 是来自 Dendrobium venustum 的天然化合物，具有抗迁移作用。Lusianthridin 通过抑制Src-STAT3 信号，促进c-Myc 的降解。体外研究
Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively.
Cell Viability Assay
| Cell Line: | The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells [1] . 0-100 μM. |
| Concentration: | 0-100 μM. |
| Incubation Time: | 24 h. |
| Result: | Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells. |