114778-60-8
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- CAS号:
- 114778-60-8
- 英文名:
- 9-(3-hydroxypropoxy)guanine
- 英文别名:
- BRL44385,BRL-44385;9-(3-hydroxypropoxy)guanine;6H-Purin-6-one, 2-amino-1,9-dihydro-9-(3-hydroxypropoxy)-
- 中文名:
- 114778-60-8
- 中文别名:
- 化合物 T10615
- CBNumber:
- CB01350603
- 分子式:
- C8H11N5O3
- 分子量:
- 225.2
- MOL File:
- 114778-60-8.mol
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114778-60-8化学性质
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密度:
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1.77±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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9.32±0.20(Predicted)
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114778-60-8性质、用途与生产工艺
BRL44385 有效且选择性地抑制单纯疱疹病毒 1 型和 2 型 (HSV-1 和 HSV-2)，水痘带状疱疹病毒 (VZV) 和 Epstein-Barr 病毒 (EBV) 复制。
BRL44385 is a selective antiherpesvirus agent. Following oral administration, BRL 55792 is very well absorbed and provides high and prolonged concentrations of BRL44385 in the blood. In mice 15 min and 60 min after administration of a single oral dose of BRL 55792, the concentrations of BRL44385 in the blood are considerably higher than those obtain after oral administration of either BRL44385 or BRL46720 and the bioavailability of BRL 44385 from oral BRL 55792 is 66% of that achieves with the same dose of the sodium salt of BRL44385 administered intravenously.
114778-60-8
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114778-60-8, 114778-60-8 相关搜索:
- 化合物 T10615
- 114778-60-8
- BRL44385,BRL-44385
- 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(3-hydroxypropoxy)-
- 9-(3-hydroxypropoxy)guanine