CD38 inhibitor
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- CAS号:
- 1700637-55-3
- 英文名:
- CD38 inhibitor 78c
- 英文别名:
- cd38-1;MDK7553;MDK 7553;MDK-7553;CD38IN-78c;CD38 IN-78c;CD38-IN-78c;Compound-78c;CD38 inhibitor 1;CD38 inhibitor 78c
- 中文名:
- CD38 inhibitor
- 中文别名:
- 化合物CD38 INHIBITOR 1;PERFEMIKER]CD38 INHIBITOR 78C,98%;4-[[反式-4-(2-甲氧基乙氧基)环己基]氨基]-1-甲基-6-(5-噻唑基)喹啉-2(1H)-酮;4-((反式-4-(2-甲氧基乙氧基)环己基)氨基)-1-甲基-6-(噻唑-5-基)喹啉-2(1H)-酮
- CBNumber:
- CB04667733
- 分子式:
- C22H27N3O3S
- 分子量:
- 413.53
- MOL File:
- 1700637-55-3.mol
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CD38 inhibitor化学性质
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沸点:
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589.8±50.0 °C(Predicted)
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密度:
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1.27±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO : 25 mg/mL (60.46 mM; ultrasonic and warming and heat to 60°C)
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形态:
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A solid
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酸度系数(pKa):
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3.17±0.20(Predicted)
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CD38 inhibitor性质、用途与生产工艺
CD38 inhibitor 1 (compound 78c, CD38-IN-78c, MDK-7553)是一种有效的 CD38 抑制剂，对人CD38和小鼠CD38的IC50分别为7.3 nM和1.9 nM。
| Target | Value |
mCD38
(Cell-free assay)
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1.9 nM
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hCD38
(Cell-free assay)
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7.3 nM
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CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle.
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Animal Model:
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Diet induced obese (DIO) C57Bl6 mice
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Dosage:
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30 mg/kg
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Administration:
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Orally once
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Result:
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NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.
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CD38 inhibitor
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-123999 | CD38 inhibitor
CD38 inhibitor 1 | 1700637-55-3 | 1mg | 600元 |
| 2024/04/30 | HY-123999 | CD38 inhibitor
CD38 inhibitor 1 | 1700637-55-3 | 10mM * 1mLin DMSO | 1370元 |
1700637-55-3, CD38 inhibitor 相关搜索:
- 药靶配体
- 小分子API
- 小分子抑制剂
- PERFEMIKER]CD38 INHIBITOR 78C,98%
- 4-[[反式-4-(2-甲氧基乙氧基)环己基]氨基]-1-甲基-6-(5-噻唑基)喹啉-2(1H)-酮
- 化合物CD38 INHIBITOR 1
- 4-((反式-4-(2-甲氧基乙氧基)环己基)氨基)-1-甲基-6-(噻唑-5-基)喹啉-2(1H)-酮
- 1700637-55-3
- MDK-7553
- MDK7553
- MDK 7553
- Compound-78c
- Cluster of Differentiation 38 Inhibitor
- CD38IN-78c
- CD38-IN-78c
- CD38 IN-78c
- 4- (trans 4- (2-methoxyethoxy) cyclohexyl) amino) -1-methyl-6- (thiazol-5-yl) quinoline-2 (1H) - one
- 4-[[trans-4-(2-Methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)quinolin-2(1H)-one
- CD38 inhibitor 1,Inhibitor,inhibit,CD-38 inhibitor 1
- cd38-1
- 4-((trans-4-(2-Methoxyethoxy)cyclohexyl)amino)-1-methyl-6-(thiazol-5-yl)quinolin-2(1H)-one
- 4-[[trans-4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-2(1H)-Quinolinone
- CD38 inhibitor 1 (compound 78c)
- 2(1H)-Quinolinone, 4-[[trans-4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-
- CD38 inhibitor 1
- CD38 inhibitor 78c