methyl 2-tetradecylglycidate
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- CAS号:
- 69207-52-9
- 英文名:
- methyl 2-tetradecylglycidate
- 英文别名:
- MCN-3716;NSC359682);McN3716,McN-3716;Methyl parmoxirate;Methyl palmoxirate;McN3716 (Methyl palmoxirate;methyl 2-tetradecylglycidate;2-Tetradecyloxiranecarboxylic acid methyl ester;2-Tetradecyloxirane-2-carboxylic acid methyl ester
- 中文名:
- methyl 2-tetradecylglycidate
- 中文别名:
- 帕莫酸甲酯;化合物 T11978
- CBNumber:
- CB21333011
- 分子式:
- C18H34O3
- 分子量:
- 298.46
- MOL File:
- 69207-52-9.mol
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methyl 2-tetradecylglycidate化学性质
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熔点:
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44-46 °C
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沸点:
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361.4±17.0 °C(Predicted)
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密度:
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0.944±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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methyl 2-tetradecylglycidate性质、用途与生产工艺
McN3716 是一种肉碱棕榈酰转移酶 I (CPT-1) 抑制剂。
Carnitine palmitoyltransferase I (CPT-1)
Inhibition of brain mitochondrial β-oxidation by McN3716 (Methyl palmoxirate, MEP) significantly reduces the levels of all measured HETE and epoxytrienoic acids (EET), nonenzymatic auto-oxidative metabolites of ARA, by 23% to 44% and 32% to 50% compared with vehicle-injected rats, respectively, except for 15-HETE which was unaffected. There is a significant 34% reduction in the level of 6-keto-PGF
1α
, a byproduct of PGI
2
(prostacyclin) in McN3716-treated rats. Similarly, the brain level of hydroxyeicosapentaenoic acids, nonenzymatic auto-oxidative metabolites of EPA, is reduced by 35% to 76% upon McN3716 treatment relative to vehicle.
methyl 2-tetradecylglycidate
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2023/03/20 | HY-U00159 | methyl 2-tetradecylglycidate
McN3716 | 69207-52-9 | 1 mg | 5300元 |
methyl 2-tetradecylglycidate
生产厂家
69207-52-9, methyl 2-tetradecylglycidate 相关搜索:
- 化合物 T11978
- 帕莫酸甲酯
- 69207-52-9
- McN3716,McN-3716
- NSC359682)
- McN3716 (Methyl palmoxirate
- Methyl parmoxirate
- Methyl palmoxirate
- MCN-3716
- 2-Tetradecyloxiranecarboxylic acid methyl ester
- 2-Tetradecyloxirane-2-carboxylic acid methyl ester
- methyl 2-tetradecylglycidate