3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]-

生物活性靶点体外研究体内研究 3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]- 试剂级价格

CAS号:: 204592-94-9

英文名:: 3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]-

英文别名:: LY377604;LY-377604,LY377604;3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]-

中文名:: 3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]-

中文别名:: 化合物 T15819

CBNumber:: CB35912145

分子式:: C31H32N4O4

分子量:: 524.61

MOL File:: 204592-94-9.mol

化学性质安全信息用途价格供应商 7

3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]-化学性质

沸点:: 809.4±65.0 °C(Predicted)

密度:: 1.282±0.06 g/cm3(Predicted)

酸度系数(pKa):: 13.94±0.20(Predicted)

安全信息

3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]-性质、用途与生产工艺

生物活性

LY377604 是一种人类 β3-肾上腺素受体激动剂，其 EC50 值为 2.4 nM，同时也是 β1 和 β2 肾上腺素能受体的拮抗剂。

靶点

EC50: 2.4 nM (human β ₃ -adrenergic receptor) β ₁ -adrenergic receptor, β ₂ -adrenergic receptor

LY377604 is a human β ₃ -adrenergic receptor agonist with an EC ₅₀ of 2.4 nM and also a β ₁ - and β ₂ -adrenergic receptor antagonist. LY377604 causes a maximal increase in cyclic adenosine monophosphate (cAMP) levels, but does not stimulate cAMP accumulation in CHO cells transfected with either the human β ₁ adrenergic receptor or the human β ₂ adrenergic receptor.

体内研究

Administration of LY377604 to male Long-Evans rats fed a caloric dense diet results in stimulation of lipid utilization. This is observed as a decrease in respiratory quotient and persists for about 4 h before returning to that measured from vehicle-treated rats.

3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]- 上下游产品信息

上游原料

下游产品

3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]- 试剂级价格

更新日期	产品编号	产品名称	CAS编号	包装	价格
2024/04/30	HY-13713	LY377604		1 mg	1750元
2024/04/30	HY-13713	LY377604		10 mg	6500元

3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]- 生产厂家

全球有 7家供应商 3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]-国内生产厂家

供应商	联系电话	电子邮件	国家	产品数	优势度
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	美国	19892	58
成都超九八生物科技有限公司	13348960310 13348960310	3003867561@qq.com	中国	10011	58
天津普西唐生物医药科技有限公司	010-60605840	psaitong@jm-bio.com	中国	29778	58
TargetMol中国（陶术生物）	4008200310	marketing@tsbiochem.com	中国	24017	58
苏州美石生物科技有限公司	1173954148q	meishipharma@126.com	中国	20035	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	美国	52927	58

204592-94-9, 3-Pyridinecarboxamide, 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]- 相关搜索: