207987-59-5
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- CAS号:
- 207987-59-5
- 英文名:
- RS-601
- 英文别名:
- RS-601;RS 601,RS601;Benzenebutanoic acid, 4-[5,5,6,6,6-pentafluoro-1-[[(4-fluorophenyl)sulfonyl]amino]hexyl]-
- 中文名:
- 207987-59-5
- 中文别名:
- 化合物 T12771
- CBNumber:
- CB43175578
- 分子式:
- C22H23F6NO4S
- 分子量:
- 511.48
- MOL File:
- 207987-59-5.mol
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207987-59-5化学性质
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沸点:
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563.3±60.0 °C(Predicted)
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密度:
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1.360±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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4.75±0.10(Predicted)
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207987-59-5性质、用途与生产工艺
RS-601 是有效的 leukotriene D4/thromboxane A2 双重抑制剂，具有平喘作用。
RS-601 (1-10 mg/kg) clearly inhibits the bronchoconstriction induced by intravenous administration of U-46619 and LTD4 in a dose-dependent fashion in guinea pigs. RS-1452 (10 mg/kg) significantly inhibits U-46619-induced bronchoconstriction, respectively. RS-601 significantly inhibits the late-phase response and LPS-induced AHR at a dose of 10 mg/kg, but does not affect biphasic bronchial responses. RS-601 (3 and 10 mg/kg) also clearly inhibits the AHR.
207987-59-5
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207987-59-5, 207987-59-5 相关搜索:
- C22H23F6NO4S
- 化合物 T12771
- 207987-59-5
- RS 601,RS601
- Benzenebutanoic acid, 4-[5,5,6,6,6-pentafluoro-1-[[(4-fluorophenyl)sulfonyl]amino]hexyl]-
- RS-601