（S）FTY720磷酸盐
|
|
|
- CAS号:
- 402616-26-6
- 英文名:
- (S) FTY720 PHOSPHATE
- 英文别名:
- (S)-FTY720-;(S)-FTY720-P;FTY720 (S)-Phosphate;(S) FTY720 PHOSPHATE;FTY720 (S) Phosphate,FTY720 (S)Phosphate,FTY-720 (S)-Phosphate;(2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol);1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, 1-(dihydrogen phosphate), (2S)-;2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester
- 中文名:
- （S）FTY720磷酸盐
- 中文别名:
- 化合物 T15354;(S)FTY720磷酸盐;S) FTY720磷酸酯;FTY720(S)-磷酸盐
- CBNumber:
- CB4988579
- 分子式:
- C19H34NO5P
- 分子量:
- 387.45
- MOL File:
- 402616-26-6.mol
|
|
|
（S）FTY720磷酸盐化学性质
-
熔点:
-
184-186°C
-
|
-
沸点:
-
584.2±60.0 °C(Predicted)
-
|
-
密度:
-
1.172±0.06 g/cm3(Predicted)
-
|
-
储存条件:
-
-20°C Freezer
-
|
-
溶解度:
-
DMSO: soluble0.3mg/mL, clear (warmed)
-
|
-
酸度系数(pKa):
-
1.73±0.10(Predicted)
-
|
-
形态:
-
Solid
-
|
-
颜色:
-
white to beige
-
|
（S）FTY720磷酸盐性质、用途与生产工艺
FTY720 (S)-Phosphate 是一种 S1P 受体 1 (S1PR1) 激动剂，可以用于急性肺损伤等急性炎症的研究。
FTY720 (S)-Phosphate is an agonist of S1PR1. FTY720 (S)-Phosphate (Tys, 1 µM) maintains S1PR1 protein expression, enhances the human pulmonary artery endothelial cells barrier via S1PR1, but shows no effect on inducing ubiquitination of S1PR1. FTY720 (S)-Phosphate (0.01-50 µM) also reduces β-arrestin recruitment to S1PR1.
FTY720 (S)-Phosphate (0.5 mg/kg, i.p.) preserves S1PR1 expression in mouse lungs, is protective in bleomycin-induced acute lung injury (ALI) and attenuates lung tissue leukocyte infiltration in bleomycin-injured mice.
（S）FTY720磷酸盐
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-15382 | FTY720 (S)-Phosphate | | 1 mg | 2080元 |
| 2024/04/30 | HY-15382 | （S）FTY720磷酸盐
FTY720 (S)-Phosphate | 402616-26-6 | 5mg | 5200元 |
402616-26-6, （S）FTY720磷酸盐 相关搜索:
- Metabolites & Impurities
- Inhibitors
- All Inhibitors
- 试剂盒-细胞分析试剂盒
- 化合物 T15354
- FTY720(S)-磷酸盐
- (S)FTY720磷酸盐
- S) FTY720磷酸酯
- 402616-26-6
- FTY720 (S) Phosphate,FTY720 (S)Phosphate,FTY-720 (S)-Phosphate
- 1,3-Propanediol, 2-amino-2-[2-(4-octylphenyl)ethyl]-, 1-(dihydrogen phosphate), (2S)-
- (S)-FTY720-P
- 2-(S)-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol Mono(dihydrogen phosphate) Ester
- (S)-FTY720-
- (2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]-1-(dihydrogen phosphate)-1,3-propanediol)
- FTY720 (S)-Phosphate
- (S) FTY720 PHOSPHATE