L-3,4-二羟基苯丙氨酸乙酯盐酸盐
|
|
|
- CAS号:
- 39740-30-2
- 英文名:
- L-DOPA Ethyl Ester Hydrochloride
- 英文别名:
- Etilevodopa HCl;Etilevodopa hydrochloride;O-Ethyl-DOPA Hydrochloride;L-DOPA Ethyl Ester Hydrochloride;Levodopa Ethyl Ester Hydrochloride;3-Hydroxy-L-tyrosine Ethyl Ester Hydrochloride;3-hydroxy- L-Tyrosine ethyl ester, hydrochloride (1:1);3,4-Dihydroxy-L-phenylalanine Ethyl Ester Hydrochloride;Ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride;disease,penetration,L-DOPA ethyl ester,tract,Dopamine Receptor,gastrointestinal,motor,Parkinson,fluctuations,CNS,Drug Metabolite,Etilevodopa hydrochloride,prodrug,Etilevodopa,inhibit,Inhibitor,esterases
- 中文名:
- L-3,4-二羟基苯丙氨酸乙酯盐酸盐
- 中文别名:
- 左旋多巴乙酯盐酸盐;化合物ETILEVODOPA HCL;L-3,4-二羟基苯丙氨酸乙酯盐酸盐
- CBNumber:
- CB52545269
- 分子式:
- C11H16ClNO4
- 分子量:
- 261.7
- MOL File:
- 39740-30-2.mol
|
|
|
L-3,4-二羟基苯丙氨酸乙酯盐酸盐化学性质
-
熔点:
-
51-54°C
-
|
-
储存条件:
-
Hygroscopic, Refrigerator, Under Inert Atmosphere
-
|
-
溶解度:
-
Methanol, Water
-
|
-
形态:
-
Solid
-
|
-
颜色:
-
Off-White
-
|
-
水溶解性:
-
Water: 125 mg/mL (477.65 mM)
-
|
-
稳定性:
-
Hygroscopic
-
|
L-3,4-二羟基苯丙氨酸乙酯盐酸盐性质、用途与生产工艺
Etilevodopa hydrochloride (L-Dopa ethyl ester hydrochloride) 是 Levodopa 的前药，在胃肠道中被非特异性酯酶快速水解为 Levodopa 和乙醇。Etilevodopa 用于帕金森病 (PD)的相关研究。Levodopa 是多巴胺的直接前体，有助于中枢神经系统的渗透和传递多巴胺。
Etilevodopa (L-Dopa ethyl ester) hydrochloride passes unchanged through the stomach to the duodenum, where it is rapidly hydrolyzed by local esterases to Levodopa and ethanol, and is subsequently absorbed into the blood stream as Levodopa.
Compared with standard Levodopa, Etilevodopa hydrochloride has greater solubility in the stomach, faster passage to the small intestine, and a shortened time to maximum Levodopa concentration.
用途
An active ingredient in preparations for the treatment of Parkinson鈥檚 disease.
L-3,4-二羟基苯丙氨酸乙酯盐酸盐
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-116016A | L-3,4-二羟基苯丙氨酸乙酯盐酸盐
Etilevodopa hydrochloride | 39740-30-2 | 5mg | 500元 |
| 2024/04/30 | HY-116016A | L-3,4-二羟基苯丙氨酸乙酯盐酸盐
Etilevodopa hydrochloride | 39740-30-2 | 10mM * 1mLin Water | 550元 |
39740-30-2, L-3,4-二羟基苯丙氨酸乙酯盐酸盐 相关搜索:
- Amino Acids & Derivatives, Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Chiral Reagents
- Aromatics
- Amino Acids & Derivatives
- 抑制剂
- 化合物ETILEVODOPA HCL
- 左旋多巴乙酯盐酸盐
- L-3,4-二羟基苯丙氨酸乙酯盐酸盐
- 39740-30-2
- disease,penetration,L-DOPA ethyl ester,tract,Dopamine Receptor,gastrointestinal,motor,Parkinson,fluctuations,CNS,Drug Metabolite,Etilevodopa hydrochloride,prodrug,Etilevodopa,inhibit,Inhibitor,esterases
- Etilevodopa HCl
- Ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride
- Etilevodopa hydrochloride
- 3-hydroxy- L-Tyrosine ethyl ester, hydrochloride (1:1)
- O-Ethyl-DOPA Hydrochloride
- Levodopa Ethyl Ester Hydrochloride
- 3-Hydroxy-L-tyrosine Ethyl Ester Hydrochloride
- 3,4-Dihydroxy-L-phenylalanine Ethyl Ester Hydrochloride
- L-DOPA Ethyl Ester Hydrochloride