N-Boc-N-bis(PEG3-OH)
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- CAS号:
- 2093154-01-7
- 英文名:
- N-Boc-N-bis(PEG3-OH)
- 英文别名:
- N-Boc-N-(PEG3-OH)2;N-Boc-N-bis(PEG3-OH);5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester
- 中文名:
- N-Boc-N-bis(PEG3-OH)
- 中文别名:
- N-叔丁氧羰基-N-双(三聚乙二醇-羟基);N-叔丁氧羰基-N-(三聚乙二醇-羟基)2;N-叔丁氧羰基-N-BIS(三聚乙二醇-羟基);13-羟基-2-[2-[2-[2-[2-(2-羟基乙氧基)乙氧基]乙氧基]乙基]-5,8,11-三氧杂-2-氮杂十三烷酸叔丁酯
- CBNumber:
- CB53373731
- 分子式:
- C21H43NO10
- 分子量:
- 469.57
- MOL File:
- 2093154-01-7.mol
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N-Boc-N-bis(PEG3-OH)化学性质
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沸点:
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557.6±50.0 °C(Predicted)
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密度:
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1.120±0.06 g/cm3(Predicted)
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酸度系数(pKa):
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14.06±0.10(Predicted)
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N-Boc-N-bis(PEG3-OH)性质、用途与生产工艺
N-Boc-N-bis(PEG4-OH) 是一种 PROTAC 连接桥，属于 PEG 类。N-Boc-N-bis(PEG4-OH) 可用于合成一系列 PROTAC 分子。N-Boc-N-bis(PEG4-OH) 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
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Cleavable
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PEGs
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Alkyl/ether
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
N-Boc-N-bis(PEG3-OH)
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2093154-01-7, N-Boc-N-bis(PEG3-OH) 相关搜索:
- C21H43NO10
- N-叔丁氧羰基-N-(三聚乙二醇-羟基)2
- N-叔丁氧羰基-N-BIS(三聚乙二醇-羟基)
- N-叔丁氧羰基-N-双(三聚乙二醇-羟基)
- 13-羟基-2-[2-[2-[2-[2-(2-羟基乙氧基)乙氧基]乙氧基]乙基]-5,8,11-三氧杂-2-氮杂十三烷酸叔丁酯
- 2093154-01-7
- 5,8,11-Trioxa-2-azatridecanoic acid, 13-hydroxy-2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]-, 1,1-dimethylethyl ester
- N-Boc-N-bis(PEG3-OH)
- N-Boc-N-(PEG3-OH)2