MMAF SODIUM
|
|
|
- CAS号:
- 1799706-65-2
- 英文名:
- L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, sodium salt (1:1)
- 英文别名:
- MMAF sodium;Monomethylauristatin F sodium;L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, sodium salt (1:1)
- 中文名:
- MMAF SODIUM
- 中文别名:
- 化合物 T16122
- CBNumber:
- CB65489101
- 分子式:
- C39H66N5NaO8
- 分子量:
- 755.97
- MOL File:
- 1799706-65-2.mol
|
|
|
MMAF SODIUM化学性质
-
储存条件:
-
Store at -20°C,unstable in solution, ready to use.
-
|
-
溶解度:
-
DMSO: ≥ 200 mg/mL (265.27 mM)
-
|
MMAF SODIUM性质、用途与生产工艺
MMAF sodium (Monomethylauristatin F sodium) 是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂，用作抗肿瘤药物。MMAF sodium (Monomethylauristatin F sodium) 广泛用作抗体偶联药物 (ADCs) 的细胞毒性成分，如Vorsetuzumab mafodotin 和 SGN-CD19A。
MMAF inhibits anaplastic large cell lymphoma Karpas 299, breast carcinoma H3396, renal cell carcinoma 786-O and Caki-1 cells with IC
50
s of 119, 105, 257 and 200 nM in vitro cytotoxicity assay.
MMAF SODIUM
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-15579B | MMAF SODIUM
MMAF sodium | 1799706-65-2 | 10mg | 560元 |
| 2024/04/30 | HY-15579B | MMAF SODIUM
MMAF sodium | 1799706-65-2 | 50mg | 1280元 |
1799706-65-2, MMAF SODIUM 相关搜索:
- C39H65N5O8Na
- 化合物 T16122
- 1799706-65-2
- Monomethylauristatin F sodium
- MMAF sodium
- L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, sodium salt (1:1)