红霉素A 9,11-亚胺醚
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- CAS号:
- 161193-44-8
- 英文名:
- ErythroMycin A 9,11-IMino Ether
- 英文别名:
- 9,11-Imino Ether;Reaxys ID: 8034880;Azithromycin Impurity 3;Azithromycin EP Impurity S;Azithromycin CP Impurity R;ErythroMycin A 9,11-IMino Ether;Azithromycin Impurity R
Erythromycin A;ErythroMycin A 9,11-IMino Ether USP/EP/BP;Azithromycin Impurity 18(Azithromycin Impurity R);Azithromycin Impurity R
Erythromycin A (9,11-Imino Ether)
- 中文名:
- 红霉素A 9,11-亚胺醚
- 中文别名:
- 红霉素亚胺醚;9,11-亚氨基醚;阿奇霉素CP杂质R;阿奇霉素EP杂质R;阿奇霉素中国药典杂质R;阿奇霉素CHP:杂质R;红霉素A 9,11-亚胺醚;红霉素A 9,11-亚氨基醚;阿奇霉素杂质18(阿奇霉素杂质R);阿奇霉素杂质R红霉素A肟(9,11-亚氨基醚)
- CBNumber:
- CB82695860
- 分子式:
- C37H66N2O12
- 分子量:
- 730.94
- MOL File:
- 161193-44-8.mol
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红霉素A 9,11-亚胺醚化学性质
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熔点:
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130-131 °C
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沸点:
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809.2±65.0 °C(Predicted)
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密度:
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1.29±0.1 g/cm3(Predicted)
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储存条件:
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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溶解度:
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Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
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酸度系数(pKa):
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12.71±0.70(Predicted)
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形态:
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Solid
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颜色:
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White to Yellow
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稳定性:
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Hygroscopic
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红霉素A 9,11-亚胺醚性质、用途与生产工艺
红霉素A 9,11-亚胺醚降低了红霉素因为酸性降解而失去活性的问题，提高了血药浓度，大大延长了半衰期，被用于呼吸道、皮肤、泌尿系统和软组织感染的药物。该药已被列入《国家基本药品名录》，具有广阔的市场前景。目前我国年产阿奇霉素超过1000吨，是世界上阿奇霉素主要的生产国。阿奇霉素重排杂质R是阿奇霉素中国药典中重要的杂质，其是阿奇霉素关键中间体红霉素A 6,9-亚胺醚的同分异构体。
红霉素A 9,11-亚胺醚
上下游产品信息
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161193-44-8, 红霉素A 9,11-亚胺醚 相关搜索:
- Pharmaceuticals, Intermediates & Fine Chemicals
- 化学试剂
- 杂质对照品
- 对照品-杂质对照品
- 杂质-阿奇霉素标准品
- 阿奇霉素杂质 34(红霉素 A(9,11-亚氨基醚))
- 阿奇霉素杂质18(阿奇霉素杂质R)
- 阿奇霉素中国药典杂质R
- (1R,2R,3R,6R,7S,8S,9R,10S,12R,15R)-9-((((3R,4S,6R)-4-(二甲基氨基)-3-羟基-6-甲基四氢-2H- 吡喃-2-基)氧基)-3-乙基-2,10-二羟基-7-(((((2R,4R,5S,6S)-5-羟基-4-甲氧基-4,6-二甲基四氢-2H-吡喃-2-基)氧基)-2,6,8,10,12,15 - 六甲基-4,16-二氧杂-14-氮杂二环[11.2.1]十六碳-13-烯-5-酮(阿奇霉素杂质)
- 红霉素亚胺醚
- 阿奇霉素CHP:杂质R
- 红霉素A 9,11-亚氨基醚
- 9,11-亚氨基醚
- 阿奇霉素CP杂质R
- 阿奇霉素杂质R红霉素A肟(9,11-亚氨基醚)
- 阿奇霉素EP杂质R
- 红霉素A 9,11-亚胺醚
- 161193-44-8
- Azithromycin Impurity 34 (Erythromycin A (9,11-Imino Ether))
- Azithromycin CP Impurity R
- Azithromycin Impurity 18(Azithromycin Impurity R)
- (1R,2R,3R,6R,7S,8S,9R,10S,12R,15R)-9-(((3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3-ethyl-2,10-dihydroxy-7-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2,6,8,10,12,15-hexamethyl-4,16-dioxa
- Erythromycin A 9,11-Imino Ether (Azithromycin Impurity R)
- ErythroMycin A 9,11-IMino Ether USP/EP/BP
- 4,16-Dioxa-14-azabicyclo[11.2.1]hexadec-13-en-5-one, 7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15-hexamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (1R,2R,3R,6R,7S,8S,9R,10R,12R,15R)-
- Erythromycin A 9,11-Imino ether/(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-ethyl-4,5-dihydroxy-10-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,9,11,13,15-hexamethyl-7,16-dioxa-2-azabicyclo[11.2.1
- Erythromycin A 9,11-Imino Ether
(Azithromycin ChP Impurity R)
- Azithromycin EP Impurity S
- Azithromycin Impurity 3
- Azithromycin Impurity R
Erythromycin A
- 9,11-Imino Ether
- Reaxys ID: 8034880
- Azithromycin Impurity R
Erythromycin A (9,11-Imino Ether)
- ErythroMycin A 9,11-IMino Ether