178908-09-3
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- CAS号:
- 178908-09-3
- 英文名:
- UK-240455
- 英文别名:
- UK-240455;UK 240455,UK240455;Methanesulfonamide, N-(6,7-dichloro-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)-N-(2-hydroxyethyl)-
- 中文名:
- 178908-09-3
- 中文别名:
- 化合物 T13248;化合物UK-240455
- CBNumber:
- CB84796699
- 分子式:
- C11H11Cl2N3O5S
- 分子量:
- 368.19
- MOL File:
- 178908-09-3.mol
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178908-09-3化学性质
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密度:
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1.686±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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7.96±0.20(Predicted)
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178908-09-3性质、用途与生产工艺
UK-240455 是一个有效且有选择性的 N-甲基 D-天冬氨酸 (NMDA) 甘氨酸位点上的拮抗剂。
UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist. Following i.v. administration of UK-240455 to male rats, UK-240455 has a clearance of 12 mL/min/kg and a volume of distribution of 0.4 L/kg. The plasma concentration of UK-240455 decreases with an apparent half-life of 0.4 h. Analysis of urine (0 to 24 h) for unchanged UK-240455 indicates that 57% of the dose administered is excreted unchanged in the urine. The urinary clearance of UK-240455 in the rat is therefore 7 mL/min/kg. Following oral administration of UK-240455 to male rats, the apparent elimination half-life of UK-240455 from plasma following oral administration is 1.6 h.
178908-09-3
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-19391 | UK-240455 | | 1 mg | 3995元 |
178908-09-3, 178908-09-3 相关搜索:
- C11H11Cl2N3O5S
- 化合物UK-240455
- 化合物 T13248
- 178908-09-3
- UK 240455,UK240455
- Methanesulfonamide, N-(6,7-dichloro-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)-N-(2-hydroxyethyl)-
- UK-240455