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网站主页 >> CAS数据库列表 >> (4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID

(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID

生物活性 靶点 体外研究 体内研究 (4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID 试剂级价格
(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID, 872993-05-0, 结构式
(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID
CAS号:
872993-05-0
英文名:
(4Z,7S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
英文别名:
RVD1;Resolvin D1;resolvin D1, CID73755062;Resolvin D1,Resolvin D-1;Resolvin D1 Exclusive;OIWTWACQMDFHJG-CCFUIAGSSA-N;Resolvin D1 MaxSpec? Standard;(4Z,7S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid;(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID;4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-
中文名:
(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID
中文别名:
消退素D1;化合物 T13864;(4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-7,8,17-三羟基-4,9,11,13,15,19-二十二碳六烯酸
CBNumber:
CB91236229
分子式:
C22H32O5
分子量:
376.49
MOL File:
872993-05-0.mol

(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID化学性质

储存条件:
Store at -80°C,protect from light
溶解度:
DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml
安全信息

(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID性质、用途与生产工艺

生物活性

Resolvin D1 (RvD1) 是炎症的一种内源性促分解介质，衍生自在急性炎症的缓解阶段的 omega-3二十二碳六烯酸。Resolvin D1 通过调节肌动蛋白聚合来阻止促炎性中性粒细胞迁移，减少巨噬细胞中 TNF-α 介导的炎症，并增强巨噬细胞对凋亡细胞的吞噬作用。

靶点

Human Endogenous Metabolite

体外研究

Resolvin D1 (RvD1) (1-100 nM; 15 minutes) induces dose-dependent short-term functional changes in primary human macrophages. RvD1 triggers intracellular Ca 2+ release, blocks chemotactic migration, and stimulates phagocytosis of microbial particles with maximal efficiency at 10 nM. Resolvin D1 (0-500 nM; 72 hours) shows a strong inhibition of LPS-induced TRAP and cathepsin K expression by RvD1 at different concentrations in RAW264.7 macrophages.

体内研究

Resolvin D1 (RvD1) (100-1000 ng; i.p.; daily on days 10) improves RA (rheumatoid arthritis) clinical endpoints in arthritic mice.

Animal Model: 18-20 g thirty 8-week-old female DBA/1J mice (collagen antibody-induced arthritis (CAIA))
Dosage: 100, 500, and 1000 ng (or 1000 ng, daily on days 4-10)
Administration: i.p. injection; daily on days 10
Result: Exhibit a reduced arthritic score.

(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID 上下游产品信息

上游原料

下游产品

(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID 试剂级价格

更新日期产品编号产品名称CAS编号包装价格
2024/04/30HY-125527(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID
Resolvin D1		872993-05-025μg(265.6μM * 250μL in Ethanol)8500元

(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID 生产厂家

全球有 23家供应商   (4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID国内生产厂家
供应商联系电话电子邮件国家产品数优势度
上海阿拉丁生化科技股份有限公司 400-400-6206333 18521732826 market@aladdin-e.com 中国 25014 65
上海一飞生物科技有限公司 021-65675885 18964387627 info@efebio.com 中国 9709 58
济南药研药物化学有限公司 jnyaoyan@163.com 中国 3069 58
上海宏叶生物科技有限公司 400-9205774 sales@glpbio.cn 中国 6870 58
南京美韬医药科技有限公司 meitaochem@126.com meitaochem@126.com 中国 19105 58
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 marketing@targetmol.com 美国 19892 58
ChemeGen 中国 18818260767 sales@chemegen.com 中国 11289 58
天津普西唐生物医药科技有限公司 010-60605840 psaitong@jm-bio.com 中国 29778 58
上海优宁维生物科技股份有限公司 18768175414 gaojun@univ-bio.com 中国 24998 58
武汉艾美捷科技有限公司 027-59626688 18771149750 sales@amyjet.com 中国 3004 58
TargetMol中国（陶术生物） 4008200310 marketing@tsbiochem.com 中国 24017 58
 

872993-05-0, (4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID 相关搜索:

胆固醇酯酶 α－法呢烯 雌四醇 乙胺
  • 生化试剂
  • 试剂盒-细胞分析试剂盒
  • C22H32O5
  • 化合物 T13864
  • 消退素D1
  • (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-7,8,17-三羟基-4,9,11,13,15,19-二十二碳六烯酸
  • 872993-05-0
  • Resolvin D1,Resolvin D-1
  • Resolvin D1 MaxSpec? Standard
  • 4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-
  • Resolvin D1 Exclusive
  • OIWTWACQMDFHJG-CCFUIAGSSA-N
  • resolvin D1, CID73755062
  • (4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID
  • RVD1
  • Resolvin D1
  • (4Z,7S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
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