m-PEG5-succinimidyl carbonate
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- CAS号:
- 1058691-00-1
- 英文名:
- m-PEG5-succinimidyl carbonate
- 英文别名:
- m-PEG5-succinimidyl carbonate;14-methoxy-3,6,9,12-tetraoxa tetradecanyl N-succinimidyl carbonate;2,5,8,11,14,17-Hexaoxaoctadecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- 中文名:
- m-PEG5-succinimidyl carbonate
- 中文别名:
- 甲氧基-五聚乙二醇-琥珀酰亚胺碳酸盐
- CBNumber:
- CB93373663
- 分子式:
- C16H27NO10
- 分子量:
- 393.39
- MOL File:
- 1058691-00-1.mol
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m-PEG5-succinimidyl carbonate化学性质
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沸点:
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469.3±55.0 °C(Predicted)
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密度:
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1.25±0.1 g/cm3(Predicted)
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m-PEG5-succinimidyl carbonate性质、用途与生产工艺
m-PEG5-succinimidyl carbonate 是一种不可降解 (non-cleavable) 的含 5 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。m-PEG5-succinimidyl carbonate 是一种 PROTAC linker，属于 PEG/Alkyl/ether 类，可用于合成 PROTAC 分子。
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PEGs
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Alkyl/ether
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Non-cleavable
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
m-PEG5-succinimidyl carbonate
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1058691-00-1, m-PEG5-succinimidyl carbonate 相关搜索:
- 甲氧基-五聚乙二醇-琥珀酰亚胺碳酸盐
- 1058691-00-1
- 14-methoxy-3,6,9,12-tetraoxa tetradecanyl N-succinimidyl carbonate
- 2,5,8,11,14,17-Hexaoxaoctadecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- m-PEG5-succinimidyl carbonate