AR-C102222 HYDROCHLORIDE
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- CAS号:
- 1781934-50-6
- 英文名:
- AR-C102222 hydrochloride
- 英文别名:
- AR-C102222 hydrochloride;ARC102222 hydrochloride,AR C102222 hydrochloride,AR-C-102222 hydrochloride
- 中文名:
- AR-C102222 HYDROCHLORIDE
- 中文别名:
- 化合物 T10361
- CBNumber:
- CB95821391
- 分子式:
- C19H17ClF2N6O
- 分子量:
- 418.83
- MOL File:
- 1781934-50-6.mol
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AR-C102222 HYDROCHLORIDE化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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AR-C102222 HYDROCHLORIDE性质、用途与生产工艺
AR-C102222 hydrochloride 是一种有效的、竞争性的、有口服活性的、高度选择性的诱导型一氧化氮合酶 (iNOS) 抑制剂，IC50 值为 37 nM。AR-C102222 hydrochloride 具有镇痛和抗炎活性。
AR-C102222 (3, 10, 30, 100 mg/kg, P.O.) attenuates arachidonic acid-induced ear inflammation and possesses anti-inflammatory activity.
AR-C102222 shows good efficacy in a rat adjuvant-induced arthritis model.
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Animal Model:
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Male Balb/c mice (20-25 g).
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Dosage:
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3, 10, 30, 100 mg/kg.
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Administration:
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P.O. 55 min before the administration of 0.6% acetic acid (i.p., 1 mL/100 g volume).
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Result:
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Significantly inhibited arachidonic acid-induced ear inflammation following a dose of 100 mg/kg of has a maximal inhibition of approximately 79%.
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AR-C102222 HYDROCHLORIDE
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-12122A | AR-C102222 HYDROCHLORIDE
AR-C102222 hydrochloride | 1781934-50-6 | 5mg | 2800元 |
| 2024/04/30 | HY-12122A | AR-C102222 hydrochloride | | 25 mg | 9000元 |
AR-C102222 HYDROCHLORIDE
生产厂家
1781934-50-6, AR-C102222 HYDROCHLORIDE 相关搜索:
- 化合物 T10361
- 1781934-50-6
- ARC102222 hydrochloride,AR C102222 hydrochloride,AR-C-102222 hydrochloride
- AR-C102222 hydrochloride