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PAPP

PAPP Structure
PAPP structure
CAS No.
1814-64-8
Chemical Name:
PAPP
Synonyms
163;LY165;LY 165;LY-165;p-Nh2-pe-tfmpp;PAPP (LY-165,163) SELECTIVE 5-HT1A SERO;1-(2-(4-Aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine;4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzenamine;Benzenamine, 4-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)-;PAPP, p-Aminophenethyl-m-trifluoromethylphenyl piperazine, 4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzeneamine
CBNumber:
CB0504467
Molecular Formula:
C19H22F3N3
Molecular Weight:
349.39
MDL Number:
MFCD00055098
MOL File:
1814-64-8.mol
Last updated:2023-05-21 08:28:49
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PAPP Properties

Melting point 83-85 °C
Boiling point 464.1±45.0 °C(Predicted)
Density 1.218±0.06 g/cm3(Predicted)
solubility 0.1 M HCl: slightly soluble
form solid
pka 7.85±0.10(Predicted)
color off-white
FDA UNII 8HAJ699EWG

SAFETY

Risk and Safety Statements

WGK Germany  3

PAPP price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S009 LY-165,163 solid 1814-64-8 25mg $125 2024-03-01 Buy
TRC L503103 LY-165,163 1814-64-8 1mg $55 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000552 LY-165,163 95.00% 1814-64-8 25MG $630.76 2021-12-16 Buy
Product number Packaging Price Buy
S009 25mg $125 Buy
L503103 1mg $55 Buy
BRS0000552 25MG $630.76 Buy

PAPP Chemical Properties,Uses,Production

Uses

LY-165,163 is a selective 5-HT1A and 5-HT1D serotonin receptor antagonist.

Definition

ChEBI: LY-165163 is a N-arylpiperazine that is piperazine susbtituted by 2-(4-aminophenyl)ethyl and 3-(trifluoromethyl)phenyl groups at positions 1 and 4, respectively. It is a selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist. It has a role as a geroprotector and a serotonergic agonist. It is a N-arylpiperazine, a N-alkylpiperazine, a member of (trifluoromethyl)benzenes, a substituted aniline and a primary arylamine. It is functionally related to a 1-(3-(trifluoromethyl)phenyl)piperazine.

PAPP synthesis

2195-13-3
1814-64-8
Synthesis of PAPP from Piperazine, 1-[2-(4-nitrophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]-

PAPP Preparation Products And Raw materials

Raw materials

Piperazine, 1-[2-(4-nitrophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]-

Preparation Products

PAPP Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1249 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Energy Chemical 58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
PAPP (LY-165,163) SELECTIVE 5-HT1A SERO PAPP, p-Aminophenethyl-m-trifluoromethylphenyl piperazine, 4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzeneamine 4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzenamine 1-(2-(4-Aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine Benzenamine, 4-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)- p-Nh2-pe-tfmpp 163 LY 165 LY165 LY-165 1814-64-8 C19H22F3N3