ChemicalBook >> CAS DataBase List >>Tanomastat
Tanomastat
- CAS No.
- 179545-77-8
- Chemical Name:
- Tanomastat
- Synonyms
- D03802;TANOMASTAT;Tanomastat (usan/inn);(S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid;(S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid;1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid;[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-;(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid
- CBNumber:
- CB0506810
- Molecular Formula:
- C23H19ClO3S
- Molecular Weight:
- 410.91
- MDL Number:
- MFCD00948600
- MOL File:
- 179545-77-8.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:03:09
| Melting point | 110-110.5°C |
|---|---|
| Boiling point | 620.1±55.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 4.01±0.23(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 179545-77-8 |
| FDA UNII | AM1ZX94EXH |
| NCI Drug Dictionary | tanomastat |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
Tanomastat price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19258 | Tanomastat ≥98% | 179545-77-8 | 500μg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19258 | Tanomastat ≥98% | 179545-77-8 | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 19258 | Tanomastat ≥98% | 179545-77-8 | 5mg | $213 | 2024-03-01 | Buy |
| Cayman Chemical | 19258 | Tanomastat ≥98% | 179545-77-8 | 10mg | $388 | 2024-03-01 | Buy |
| TRC | T006900 | Tanomastat | 179545-77-8 | 5mg | $180 | 2021-12-16 | Buy |
Tanomastat Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor. Optical Rotation +82?(C 1.5 acetone)
Uses
A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor.Optical Rotation +82° (C 1.5 acetone).
Uses
Tanomastat is an orally available, non-peptidic inhibitor of matrix metalloproteinase-2 (MMP-2), MMP-3, and MMP-9 (Kis = 11, 143, and 301 nM, respectively). It is active in various animal models of tumor metastasis and has been used in a phase III clinical trial in pancreatic, SCLC, NSCLC, and ovarian cancer patients.
Definition
ChEBI: Tanomastat is an organochlorine compound and a member of biphenyls.
Tanomastat Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
179545-77-8(Tanomastat)Related Search:
TANOMASTAT
BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid
(S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid
(S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid
D03802
Tanomastat (usan/inn)
(S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid
[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-
1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-
179545-77-8
C23H19ClO3S
Chiral Reagents
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals
Sulfur & Selenium Compounds