oxyacanthine
- CAS No.
- 548-40-3
- Chemical Name:
- oxyacanthine
- Synonyms
- vinetine;Oxycanthine;oxyacanthine;6,6',7-Trimethoxy-2,2'-dimethyloxyacanthan-12'-ol;2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-9-ol, 3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-
- CBNumber:
- CB0902883
- Molecular Formula:
- C37H40N2O6
- Molecular Weight:
- 608.72
- MDL Number:
- MOL File:
- 548-40-3.mol
| Melting point | 216-217° |
|---|---|
| alpha | D20 +131.5° (chloroform) |
| Boiling point | 655.15°C (rough estimate) |
| Density | 1.1648 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| pka | 9.42±0.20(Predicted) |
| FDA UNII | 5BD0KNF4AT |
oxyacanthine Chemical Properties,Uses,Production
Description
This alkaloid was first obtained by Hesse from Berberis vulgaris and is also a minor constituent of other Berberis and Mahonia species. When recrystallized from EtOH it forms clusters of colourless needles, m.p. 208-214°C, the higher melting point given above being obtained in vacuo. It has [α]D + 131.6° (CHC13), a much higher value of + 279° (CHCI3) being given by Gericke and Bruchhausen. The dihydrochloride forms needles, m.p. 270-1°C (vac.); [α] +29 D+ 188.5° (H20) and is only sparingly soluble in dilute HC1; the hydrobromide has m.p. 273-5°C (dec., vac.) and the nitrate forms colourless needles, m.p. 195- 200°C (dec.). The presence of the phenolic hydroxyl group is indicated by the formation of an O-benzoy1 derivative, a potassium salt and the O-methyl ether, giving a hydrochloride, m.p. 261°C. The structure has been deduced from chem_x0002_ical and spectroscopic data. Various colour reactions have been described, e.g. the alkaloid is not coloured by H2S04, gives a yellow colour with HN03 and with molybdic acid in H2S04 produces a violet colour, slowly changing to yellow-green.
Definition
ChEBI: A macrocycle that is oxyacanthan that is substituted by methoxy groups at positions 6, 6', and 7, methyl groups at positions 2 and 2', and a hydroxy group at the 12' position.
oxyacanthine Preparation Products And Raw materials
Raw materials
Preparation Products
oxyacanthine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Interbioscreen Ltd. | -- | screen@ibscreen.chg.ru | Finland | 6178 | 60 |
| Supplier | Advantage |
|---|---|
| Interbioscreen Ltd. | 60 |