ChemicalBook >> CAS DataBase List >>1,2,3,5-Tetrachlorobenzene

1,2,3,5-Tetrachlorobenzene

CAS No.
634-90-2
Chemical Name:
1,2,3,5-Tetrachlorobenzene
Synonyms
1,2,3,5-tcb;1,2,3,5-Tetrachlorob;1,3,4,5-Tetrachlorbenzol;,2,3,5-TETRACHLOROBENZENE;Nicotinamide Impurity 249;1,2,3,5-TETRACHLOROBENZENE;tetrachloro1,2,3,5-benzene;1,2,4,6-tetrachlorobenzene;1,2,3,5-tetrachloro-benzen;1,3,4,5-Tetrachlorobenzene
CBNumber:
CB1395743
Molecular Formula:
C6H2Cl4
Molecular Weight:
215.89
MDL Number:
MFCD00000543
MOL File:
634-90-2.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:39

1,2,3,5-Tetrachlorobenzene Properties

Melting point 54.5°C
Boiling point 246°C
Density 1.5578 (estimate)
vapor pressure 0.07 at 25 °C (extrapolated, Mackay et al., 1982)
refractive index 1.5348 (estimate)
Flash point 113 °C
storage temp. APPROX 4°C
solubility Soluble in alcohol, benzene, ether, and ligroin (Weast, 1986)
color White to Almost white
Water Solubility 4.016mg/L(25 ºC)
BRN 1618864
Henry's Law Constant 58.0 at 25 °C (gas stripping-GC, Shiu and Mackay, 1997)
CAS DataBase Reference 634-90-2(CAS DataBase Reference)
FDA UNII I27N186CIN
NIST Chemistry Reference Benzene, 1,2,3,5-tetrachloro-(634-90-2)
EPA Substance Registry System 1,2,3,5-Tetrachlorobenzene (634-90-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H410
Precautionary statements  P264-P270-P273-P301+P312-P391-P501
Hazard Codes  Xn,T,F
Risk Statements  22-39/23/24/25-23/24/25-11
Safety Statements  22-24/25-45-36/37-16-7
RIDADR  UN 1230 3/PG 2
WGK Germany  3
RTECS  DB9445000
HS Code  2903.99.8001
Toxicity Acute oral LD50 for rats 1,727 mg/kg (quoted, RTECS, 1985).
NFPA 704
1
1 0

1,2,3,5-Tetrachlorobenzene price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 36928 1,2,3,5-Tetrachlorobenzene PESTANAL 634-90-2 250mg $40 2024-03-01 Buy
TCI Chemical T0870 1,2,3,5-Tetrachlorobenzene 634-90-2 5G $153 2024-03-01 Buy
TCI Chemical T0870 1,2,3,5-Tetrachlorobenzene 634-90-2 25G $425 2024-03-01 Buy
TRC T291995 1,2,3,5-Tetrachlorobenzene 634-90-2 10g $185 2021-12-16 Buy
Matrix Scientific 098293 1,2,3,5-Tetrachlorobenzene 95+% 634-90-2 10g $238 2021-12-16 Buy
Product number Packaging Price Buy
36928 250mg $40 Buy
T0870 5G $153 Buy
T0870 25G $425 Buy
T291995 10g $185 Buy
098293 10g $238 Buy

1,2,3,5-Tetrachlorobenzene Chemical Properties,Uses,Production

Uses

1,2,3,5-Tetrachlorobenzene is used in the synthesis of several organic compounds including that of polyarylated benzenes by multiple Suzuki-Miyaura reactions. It was used as part of study which investigated the antimicrobial activity of tetra substituted benzene derivatives which suggested antimicrobial activity tended to decrease with increasing size of halogen substituents.

Definition

ChEBI: A tetrachlorobenzene carrying chloro groups at positions 1, 2, 3 and 5.

General Description

White crystals or off-white solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Simple aromatic halogenated organic compounds, such as 1,2,3,5-Tetrachlorobenzene , are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. 1,2,3,5-Tetrachlorobenzene may react with oxidizers. .

Health Hazard

ACUTE/CHRONIC HAZARDS: 1,2,3,5-Tetrachlorobenzene may cause irritation on contact.

Fire Hazard

1,2,3,5-Tetrachlorobenzene is probably combustible.

Environmental Fate

Biological. A mixed culture of soil bacteria or a Pseudomonas sp. transformed 1,2,3,5-tetrachlorobenzene to 2,3,4,6-tetrachlorophenol (Ballschiter and Scholz, 1980). The half-life of 1,2,3,5- tetrachlorobenzene in an anaerobic enrichment culture was 1.8 d (Beurskens et al., 1993).
In an enrichment culture derived from a contaminated site in Bayou d’Inde, LA, 1,2,3,5- tetrachlorobenzene underwent reductive dechlorination to 1,2,4- and 1,3,5-trichlorobenzene at relative molar yields of 7 and 93%, respectively. The maximum dechlorination rate, based on the recommended Michaelis-Menten model, was 94 nM/d (Pavlostathis and Prytula, 2000).
Photolytic. Irradiation (λ ≥285 nm) of 1,2,3,5-tetrachlorobenzene (1.1–1.2 mM/L) in an acetonitrile-water mixture containing acetone (0.553 mM/L) as a sensitizer gave the following products (% yield): 1,2,3-trichlorobenzene (5.3), 1,2,4-trichlorobenzene (4.9), 1,3,5-trichlorobenzene (49.3), 1,3-dichlorobenzene (1.8), 2,3,4,4′,5,5′,6-heptachlorobiphenyl (1.41), 2,2′,3,4,4′,6,6′- heptachlorobiphenyl (1.10), 2,2′,3,3′,4,5′,6-heptachlorobiphenyl (4.50), four hexachlorobiphenyls (4.69), one pentachlorobiphenyl (0.64), trichloroacetophenone, 1-(trichlorophenyl)-2-propanone, and (trichlorophenyl)acetonitrile (Choudhry and Hutzinger, 1984). Without acetone, the identified photolysis products (% yield) included 1,2,3-trichlorobenzene (trace), 1,2,4-trichlorobenzene (24.3), 1,3,5-trichlorobenzene (11.7), 1,3-dichlorobenzene (0.5), 1,4-dichlorobenzene (3.3), pentachlorobenzene (1.43), 1,2,3,4-tetrachlorobenzene (5.99), two heptachlorobiphenyls (1.40), two hexachlorobiphenyls (<0.01), and one pentachlorobiphenyl (0.75) (Choudhry and Hutzinger, 1984).

Purification Methods

Crystallise it from EtOH. [Beilstein 5 II 157, 5 III 551, 5 IV 668.]

95-50-1
634-90-2
Synthesis of 1,2,3,5-Tetrachlorobenzene from 1,2-Dichlorobenzene
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View Lastest Price from 1,2,3,5-Tetrachlorobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,2,3,5-Tetrachlorobenzene pictures 2019-07-06 1,2,3,5-Tetrachlorobenzene
634-90-2
US $1.00 / kg 1kg 95%-99% as request Career Henan Chemical Co
1,2,3,5-tcb 1,2,3,5-tetrachloro-benzen 1,2,4,6-tetrachlorobenzene benzene,1,2,3,5-tetrachloro- chlorinatedbenzenes,tri-,tetra-andpenta- tetrachloro1,2,3,5-benzene 1,2,3,5-TETRACHLOROBENZENE OEKANAL, 250 1,2,3,5-TETRACHLOROBENZENE, 1X1ML MEOH 2 000UG/ML 1,2,3,5-TETRACHLOROBENZENE ,2,3,5-TETRACHLOROBENZENE 1,2,3,5-tcb 1,2,4,6-tetrachlorobenzene 1,2,3,5-Tetrachlorob 1,2,3,5-tetrachlorobenzene solution 1,3,4,5-Tetrachlorbenzol 1,2,3,5-tcb 1,2,4,6-tetrachlorobenzene 1,3,4,5-Tetrachlorbenzol 1,2,3,5-Tetrachlorobenzene 10 μg/mL in Cyclohexane 1,3,4,5-Tetrachlorobenzene 1,2,3,5-Tetrachlorobenzene > Nicotinamide Impurity 249 634-90-2 643-90-2 C6H2Cl4 FINE Chemical & INTERMEDIATES Benzene derivates Pesticides&Metabolites Q-ZAlphabetic Single Component Standards for MISA AnalysesVolatiles/ Semivolatiles Alpha Sort Canada International Standards TA - TE T-ZAlphabetic