ChemicalBook >> CAS DataBase List >>Tyrphostin AG1433
Tyrphostin AG1433
- CAS No.
- 168835-90-3
- Chemical Name:
- Tyrphostin AG1433
- Synonyms
- 1,2-Benzenediol, 4-(6,7-dimethyl-2-quinoxalinyl)-;cytotoxicity,PDGFRβ,Tyrphostin AG 1433,AG-1433,Tyrphostin AG1433,VEGFR,AG 1433,kinases,Vascular endothelial growth factor receptor,SU 1433,Tyrphostin AG-1433,Platelet-derived growth factor receptor,angiogenesis,tyrosine,inhibit,VEGFR-2,Inhibitor,ATM,PDGFR,SU-1433
- CBNumber:
- CB15854618
- Molecular Formula:
- C16H14N2O2
- Molecular Weight:
- 266.29
- MDL Number:
- MOL File:
- 168835-90-3.mol
Last updated:2023-09-04 15:51:00
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
Tyrphostin AG1433 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0077937 | TyrphostinAG1433 99.20% | 168835-90-3 | 5mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-0077937 | TyrphostinAG1433 99.20% | 168835-90-3 | 10mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-0077937 | TyrphostinAG1433 99.20% | 168835-90-3 | 50mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-0077937 | TyrphostinAG1433 99.20% | 168835-90-3 | 100mg | $1050 | 2021-12-16 | Buy |
| DC Chemicals | 012455 | TyrphostinAG1433 | 168835-90-3 | 003 | $1800 | 2021-12-16 | Buy |
Tyrphostin AG1433 Chemical Properties,Uses,Production
Biological Activity
Tyrphostin AG1433 (SU1433) is a tyrosine kinase inhibitor. It is also a selective PDGFRβ and VEGFR-2 (Flk-1/KDR) inhibitor with IC50 of 5.0 μM and 9.3 μM, respectively. It prevents blood vessel formation.
in vivo
Chorion allantoic membrane (CAM) assays are used to determine the effects of the Flk-i inhibitors on angiogenesis. Tyrphostin AG1433 (SU1433) is prepared in methylcellulose pellets and applies to the CAMs of 4-6-day- old chicken embryos. Tyrphostin AG1433 prevents the formation of new yessels under the pellets.
target
| Flk-1 < span> 9.3 μM (IC 50 ) | PDGFRβ 5 μM (IC 50 ) |
Tyrphostin AG1433 Preparation Products And Raw materials
Raw materials
Preparation Products
Tyrphostin AG1433 Suppliers
Global( 21)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3501 | 55 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 2853979815@qq.com | China | 10018 | 55 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shandong Jirun Biomedical Technology Co., Ltd. | 0539-0539-8613587 17661611089 | 2639273505@qq.com | China | 163 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
| Hefei Mokai Pharmaceutical Technology Co., Ltd | 18130062233 | 3362556465@qq.com | China | 8000 | 58 |
168835-90-3(Tyrphostin AG1433)Related Search:
1,2-Benzenediol, 4-(6,7-dimethyl-2-quinoxalinyl)-
cytotoxicity,PDGFRβ,Tyrphostin AG 1433,AG-1433,Tyrphostin AG1433,VEGFR,AG 1433,kinases,Vascular endothelial growth factor receptor,SU 1433,Tyrphostin AG-1433,Platelet-derived growth factor receptor,angiogenesis,tyrosine,inhibit,VEGFR-2,Inhibitor,ATM,PDGFR,SU-1433
168835-90-3