Dicentrin
- CAS No.
- 517-66-8
- Chemical Name:
- Dicentrin
- Synonyms
- Nsc406035;dicentrine;DICENTRINE95%;(S)-dicentrine;o,N-Dimethyllitseferine;1,2-Methylenedioxy-9,10-dimethoxyaporphine;9,10-Dimethoxy-1,2-(methylenedioxy)aporphine;9,10-Dimethoxy-1,2-(methylenedioxy)-6aalpha-aporphine;1,2-(Methylenedioxy)-9,10-dimethoxy-6aalpha-aporphine;6A.alpha.-Aporphine, 9,10-dimethoxy-1,2-(methylenedioxy)-
- CBNumber:
- CB21178489
- Molecular Formula:
- C20H21NO4
- Molecular Weight:
- 339.39
- MDL Number:
- MFCD00210492
- MOL File:
- 517-66-8.mol
- MSDS File:
- SDS
| Melting point | 177-178℃ |
|---|---|
| Boiling point | 481℃ |
| Density | 1.266 |
| refractive index | 1.6250 (estimate) |
| Flash point | 143℃ |
| storage temp. | 4°C, protect from light |
| solubility | Soluble in DMSO |
| pka | 6.65±0.20(Predicted) |
| FDA UNII | J2ZGT5M0N7 |
Dicentrin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0026026 | Dicentrine | 517-66-8 | 1mg | $171 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0016457 | DICENTRINE 95.00% | 517-66-8 | 5MG | $504.69 | 2021-12-16 | Buy |
| ChemScene | CS-0026026 | Dicentrine | 517-66-8 | 5mg | $514 | 2021-12-16 | Buy |
| AvaChem | 2300 | Dicentrine | 517-66-8 | 20mg | $690 | 2021-12-16 | Buy |
| AvaChem | 2300 | Dicentrine | 517-66-8 | 100mg | $1690 | 2021-12-16 | Buy |
Dicentrin Chemical Properties,Uses,Production
Description
D-Dicentrine is an aporphinic alkaloid found in several plant species, mainly from family Lauraceae, including Lindera megaphylla. D-Dicentrine shows antinociceptive activity in a mouse model of pain. It probably acts via a TRPA1-dependent mechanism. D-Dicentrine is an alpha 1-adrenoceptor antagonist effective against human hyperplastic prostates.
Anti-cancer Activity
D-Dicentrine, a naturally occurring aporphine type isoquinoline alkaloid, isolated from the root of Lindera megaphylla Hemsl. (Lauraceae), was evaluated for its potential anti-cancer activity. Huang RL etc. found d-dicentrine significantly inhibited the growth of human hepatoma cell line HuH-7 by delaying its doubling time in tissue culture. An in vitro colony forming assay showed that d-dicentrine decreased the colony formation efficiency in both hepatoma cell lines, HuH-7 and MS-G2, used in our study.
Uses
d-Dicentrine is a natural aporphine alkaloid extracted from the root of L. megaphylla which displays antitumor effects through inhibition of topoisomerase II.
Definition
ChEBI: Dicentrine is an aporphine alkaloid.
Dicentrin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Huzhou ZhanShu Biotechnology Co.,Ltd | 0572-8889530 18167260939 | zsubio@163.com | China | 346 | 58 |
| Shandong Xiya Chemical Co., Ltd | 4009903999 13355009207 | 3007715519@qq.com | China | 18739 | 57 |
Related articles
- D-Dicentrine – a naturally occurring aporphine type isoquinoline alkaloid
- D-Dicentrine is an aporphinic alkaloid found in several plant species, mainly from family Lauraceae, including Lindera megaphy....
- Dec 23，2019