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ChemicalBook >> CAS DataBase List >>(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Structure
(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol structure
CAS No.
135133-23-2
Chemical Name:
(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Synonyms
Efinaconazole Impurity F;Efinaconazole Impurity 39;(2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)...;(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 3-THP Ether;(2R,3R)-2-(2,4-difluorophenyl)-3-tetrahydropyran-2-yloxy-1-(1,2,4-triazol-1-yl)butan-2-ol;(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[(1R)-1-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]-, (αR)-;(2R,3R)-2-(2,4-difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol(WXG00770);(alphaR)-alpha-(2,4-Difluorophenyl)-alpha-[(1R)-1-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]-1H-1,2,4-triazole-1-ethanol
CBNumber:
CB22705239
Molecular Formula:
C17H21F2N3O3
Molecular Weight:
353.36
MDL Number:
MFCD31631083
MOL File:
135133-23-2.mol
Request For Quotation

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Properties

Boiling point 533.9±60.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
pka 11.61±0.29(Predicted)

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D451373 (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol3-THPEther 135133-23-2 5mg $310 2021-12-16 Buy
Product number Packaging Price Buy
D451373 5mg $310 Buy

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical Properties,Uses,Production

Uses

(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 3-THP Ether is an impurity of efinaconazole (E435070).

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol synthesis

348-57-2
135133-23-2
Synthesis of (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol from 1-Bromo-2,4-difluorobenzene

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Preparation Products And Raw materials

Raw materials

1-Propanone, 2-(acetyloxy)-1-(2,4-difluorophenyl)- 4-[(2R)-2-(3,4,5,6-tetrahydro-2H-pyran-2-yloxy)-propionyl]morpholine 1-Propanone, 1-(2,4-difluorophenyl)-2-hydroxy-, (2R)- 2-((R)-1-((R)-2-(2,4-difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran 2,4-difluoro phenyl magnesium bromide
1,2,4-Triazole 1,2,4-Triazolylsodium 1-Bromo-2,4-difluorobenzene 3,4-Dihydro-2H-pyran

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Preparation Products

(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Suppliers

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sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
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Supplier Advantage
sgtlifesciences pvt ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Aceschem Inc. 		58
China National Standard Pharmaceutical Corporation Limited 		58
Taizhou Tongxin Bio-Tech Co., Ltd 60
ChemStrong Scientific Co.,Ltd 56
Guangzhou Dreampharm Biotechnology Co., Ltd. 12
Jinan blalong chemical co. LTD 58
Guangzhou Juntang Technology Co., Ltd 58
Shenzhen Roark Pharma-Tec Co., Ltd. 58
(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (alphaR)-alpha-(2,4-Difluorophenyl)-alpha-[(1R)-1-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]-1H-1,2,4-triazole-1-ethanol Efinaconazole Impurity 39 (2R,3R)-2-(2,4-difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol(WXG00770) (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 3-THP Ether 1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[(1R)-1-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]-, (αR)- Efinaconazole Impurity F (2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)... (2R,3R)-2-(2,4-difluorophenyl)-3-tetrahydropyran-2-yloxy-1-(1,2,4-triazol-1-yl)butan-2-ol 135133-23-2 C17H21F2N3O3