ChemicalBook >> CAS DataBase List >>dBET1
dBET1
- CAS No.
- 1799711-21-9
- Chemical Name:
- dBET1
- Synonyms
- dBET1;CS-2706;DBET1;DBET-1 ;DBET 1;JQ1-Thalidomide conjugate;dBET1,inhibit,PROTACs,Epigenetic Reader Domain,Inhibitor,dBET 1,dBET-1;2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)acetamide;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-, (6S)-;N-(4-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0,2,6]trideca-2 (6),4,7,10,12-pentaen-9-yl]acetamido}butyl)-2-{[2-( 2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-i soindol-4-yl]oxy}acetamide
- CBNumber:
- CB23133361
- Molecular Formula:
- C38H37ClN8O7S
- Molecular Weight:
- 785.27
- MDL Number:
- MFCD31544503
- MOL File:
- 1799711-21-9.mol
Last updated:2023-06-30 15:45:59
dBET1 price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18044 | dBET1 ≥98% | 1799711-21-9 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 18044 | dBET1 ≥98% | 1799711-21-9 | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 18044 | dBET1 ≥98% | 1799711-21-9 | 10mg | $363 | 2024-03-01 | Buy |
| TRC | I120055 | dBET1 | 1799711-21-9 | 2.5mg | $855 | 2021-12-16 | Buy |
| TRC | I120055 | dBET1 | 1799711-21-9 | 1mg | $360 | 2021-12-16 | Buy |
dBET1 Chemical Properties,Uses,Production
Description
dBET1 is a PROTAC compound comprised of BET bromodomain antagonist (+)-JQ1 linked to a cereblon E3 ubiquitin ligase ligand.
Uses
dBET1 induces highly selective cereblon-dependent BET protein degradation in vitro and in vivo as well as delays leukemia progression in mice.
storage
Store at -20°C
dBET1 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 65)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai finete Pharmaceutical Co., Ltd. | +86-18221039705 | CHINA | 139 | 55 | |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5999 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
dBET1
DBET1;DBET-1 ;DBET 1
CS-2706
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-, (6S)-
N-(4-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0,2,6]trideca-2 (6),4,7,10,12-pentaen-9-yl]acetamido}butyl)-2-{[2-(
2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-i soindol-4-yl]oxy}acetamide
2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)acetamide
dBET1,inhibit,PROTACs,Epigenetic Reader Domain,Inhibitor,dBET 1,dBET-1
JQ1-Thalidomide conjugate
1799711-21-9
C38H37ClN8O7S